Fibronectin 1 antibody

Catalog No. ABIN969149

The Mouse Monoclonal anti-Fibronectin 1 antibody has been validated for ELISA, IHC and FACS. It is suitable to detect Fibronectin 1 in samples from Human. There are 4+ publications available.

Quick Overview for Fibronectin 1 antibody (ABIN969149)

Target: Fibronectin 1 (FN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fibronectin 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2F4

Product Details anti-Fibronectin 1 Antibody

Purpose: FN1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human FN1 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Fibronectin 1 antibody (ABIN969149)

Li, Li, Duan, Cai, You, Zhou, Yang, Tuo, Liu: "Blockage of TGF-α Induced by Spherical Silica Nanoparticles Inhibits Epithelial-Mesenchymal Transition and Proliferation of Human Lung Epithelial Cells." in: BioMed research international, Vol. 2019, pp. 8231267, (2019) (PubMed).

Guo, You, Li, Tuo, Liu: "Spherical silica nanoparticles promote malignant transformation of BEAS-2B cells by stromal cell-derived factor-1α (SDF-1α)." in: The Journal of international medical research, Vol. 47, Issue 3, pp. 1264-1278, (2019) (PubMed).

Ryschich, Khamidjanov, Kerkadze, Büchler, Zöller, Schmidt: "Promotion of tumor cell migration by extracellular matrix proteins in human pancreatic cancer." in: Pancreas, Vol. 38, Issue 7, pp. 804-10, (2009) (PubMed).

Huang, Zhang, Kim, Ge, Annis, Mosher, Greenspan: "Fibronectin binds and enhances the activity of bone morphogenetic protein 1." in: The Journal of biological chemistry, Vol. 284, Issue 38, pp. 25879-88, (2009) (PubMed).

Target Details for Fibronectin 1

Target: Fibronectin 1 (FN1)

Alternative Name: FN1

Background: This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.

Molecular Weight: 262.6 kDa

Gene ID: 2335

UniProt: P02751

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy