GRIA2 antibody (AA 652-807)

Catalog No. ABIN969524

The Mouse Monoclonal anti-GRIA2 antibody has been validated for WB, ELISA and FACS. It is suitable to detect GRIA2 in samples from Human. There are 2+ publications available.

Quick Overview for GRIA2 antibody (AA 652-807) (ABIN969524)

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRIA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 7G6

Product Details anti-GRIA2 Antibody

Binding Specificity: AA 652-807

Purpose: GRIA2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-GRIA2 antibody (ABIN969524)

Yu, Wu, Fu, Cheng, Yang, Chen, Long, Chen, Wang: "Aging-related alterations in the expression and distribution of GluR2 and PICK1 in the rat hippocampus." in: Neuroscience letters, Vol. 497, Issue 1, pp. 42-5, (2011) (PubMed).

Shen, Jin: "[GluR2 expression in the developing rat inferior colliculus and the relationship with development of synapse]." in: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, Vol. 24, Issue 4, pp. 173-6, (2010) (PubMed).

Target Details for GRIA2

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Alternative Name: GRIA2

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.

Molecular Weight: 98.8 kDa

Gene ID: 2891

UniProt: P42262

Pathways: PI3K-Akt Signaling