HSF4 antibody

Catalog No. ABIN969527

The Mouse Monoclonal anti-HSF4 antibody has been validated for ELISA and FACS. It is suitable to detect HSF4 in samples from Human. There are 2+ publications available.

Quick Overview for HSF4 antibody (ABIN969527)

Target: HSF4 (Heat Shock Transcription Factor 4 (HSF4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSF4 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 2E7

Product Details anti-HSF4 Antibody

Purpose: HSF4 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human HSF4 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-HSF4 antibody (ABIN969527)

Ma, Zhang, Li, Xi, Hu: "[Construction of eukaryotic plasmid expression Hsf4b and phosphorylation of Hsf4b by MAP kinase P38]." in: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, Vol. 26, Issue 4, pp. 325-8, (2010) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Target Details for HSF4

Target: HSF4 (Heat Shock Transcription Factor 4 (HSF4))

Alternative Name: HSF4

Background: Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.

Molecular Weight: 53 kDa

Gene ID: 3299

UniProt: Q9ULV5

Pathways: MAPK Signaling