APOBEC3H Products
(Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3H (APOBEC3H))
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This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009].
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Featured APOBEC3H Categories
APOBEC3H Antibodies
High quality antibodies with extensive validation data.
APOBEC3H Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended APOBEC3H Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN531149
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN6259988
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB
Validations
Cat. No.
ABIN6749340
Quantity
100 μL
Datasheet
Datasheet
Recommended APOBEC3H Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345363
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3087960
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Rhesus Monkey
Source
Yeast
Validations
Cat. No.
ABIN1620112
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our APOBEC3H products
: "Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease." in: Nature communications, Vol. 9, Issue 1, pp. 4137, (2019) (PubMed).: "The Role of RNA in HIV-1 Vif-Mediated Degradation of APOBEC3H." in: Journal of molecular biology, Vol. 431, Issue 24, pp. 5019-5031, (2019) (PubMed).
: "APOBEC3H Subcellular Localization Determinants Define Zipcode for Targeting HIV-1 for Restriction." in: Molecular and cellular biology, Vol. 38, Issue 23, (2018) (PubMed).
: "The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis." in: Nature communications, Vol. 7, pp. 12918, (2016) (PubMed).
: "The Structural Interface between HIV-1 Vif and Human APOBEC3H." in: Journal of virology, Vol. 91, Issue 5, (2016) (PubMed).
: "Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity." in: PLoS genetics, Vol. 10, Issue 11, pp. e1004761, (2014) (PubMed).
: "The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism." in: Molecular cell, Vol. 69, Issue 1, pp. 75-86.e9 (PubMed).
Synonyms and alternative names related to APOBEC3H
apolipoprotein B mRNA editing enzyme catalytic subunit 3H (APOBEC3H), A3H, APOBEC3A, ARP10Protein level used designations for APOBEC3H
- APOBEC-related protein 10
- ARP-10
- DNA dC->dU-editing enzyme APOBEC-3H
- apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H
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