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SARS

Before the emergence of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) in 2003, only 12 other animal or human coronaviruses were known. The discovery of this virus was soon followed by the discovery of the civet and bat SARS-CoV and the human coronaviruses NL63 and HKU1.

The explosive nature of the first SARS epidemic, the high mortality, its transient reemergence a year later, and economic disruptions led to a rush on research of the epidemiological, clinical, pathological, immunological, virological, and other basic scientific aspects of the virus and the disease.(6)

SARS Coronavirus Antibodies & Proteins used in current Research

Product
Type
Cat. No.
Validations
Delivery
Quantity
Datasheet
Type Primary
Cat. No. ABIN1169449
Validations
  • (4)
  • (5)
Delivery 5 to 8 Days
Quantity 100 μg
Datasheet Datasheet
Type Protein
Cat. No. ABIN6952431
Validations
  • (1)
  • (7)
Delivery 2 to 3 Days
Quantity 200 μg
Datasheet Datasheet
Type Primary
Cat. No. ABIN129545
Validations
  • (1)
Delivery 1 to 2 Days
Quantity 500 μg
Datasheet Datasheet
Type Primary
Cat. No. ABIN3027526
Validations
Delivery 9 to 11 Days
Quantity 1 mg
Datasheet Datasheet

COVID-19 / SARS-CoV-2 Products

Products for Coronavirus Proteins

CoV consists of four proteins with the being the most important surface protein. Find relevant products, antibodies, kits, proteins, assays:

  • Spike Protein:
  • Envelope Protein:
  • Membrane Protein:
  • Nucleocapsid Protein:

SARS-CoV Spike Protein Antibodies

The coronavirus spike contains three segments: a large ectodomain, a single-pass transmembrane anchor, and a short intracellular tail. The ectodomain consists of a receptor-binding subunit S1 and a membrane-fusion subunit S2. During virus entry, S1 binds to a receptor on the host cell surface for viral attachment, and S2 fuses the host and viral membranes, allowing viral genomes to enter host cells.(1)

Below you will find a selection of our CoV spike protein antibodies. Click on the links to see more details.

Product
Clonality
Application
Cat. No.
Quantity
Datasheet
Clonality Monoclonal
Application ELISA, WB, IF, IC
Cat. No. ABIN2452119
Quantity 50 μg
Datasheet Datasheet
Clonality Polyclonal
Application WB
Cat. No. ABIN200034
Quantity 100 μg
Datasheet Datasheet
Clonality Polyclonal
Application ELISA, WB
Cat. No. ABIN199980
Quantity 100 μg
Datasheet Datasheet
Clonality Polyclonal
Application WB
Cat. No. ABIN725442
Quantity 100 μL
Datasheet Datasheet
Clonality Polyclonal
Application ELISA
Cat. No. ABIN1031207
Quantity 0.1 mg
Datasheet Datasheet

SARS-CoV Nucleocapsid Protein Antibodies

Of all the coronaviral structural proteins, the N protein is the most abundant throughout infection, both in mRNA and protein levels. Compared to the mRNA levels of other structural genes, the mRNA of the N protein is expressed three to ten times higher at 12-hour post-infection.(2)

Below you will find a selection of our CoV SARS-CoV Nucleocapsid protein antibodies. Take a look at SARS-CoV N antibody ABIN129544. The Immunogen has 90% homology with SARS-CoV-2 Nucleocapsid.

SARS-CoV Envelope Protein Antibodies

The E protein is the smallest of the major structural proteins, but also the most enigmatic. During the replication cycle, E is abundantly expressed inside the infected cell, but only a small portion is incorporated into the virion envelope. The majority of the protein is localised at the site of intracellular trafficking.(4)

Below you will find a selection of our SARS-CoV Envelope protein antibodies. Click on the links to see more details.

Product
Clonality
Application
Cat. No.
Quantity
Datasheet
Clonality Polyclonal
Application ELISA, WB
Cat. No. ABIN199987
Quantity 100 μg
Datasheet Datasheet

SARS-CoV Membrane Protein Antibodies

The coronavirus membrane (M) protein is the key player in virion assembly. One of its functions is to mediate the incorporation of the spikes into the viral envelope. When expressed alone, it accumulates in the Golgi complex in homomultimeric complexes. However, in combination with the E protein, virus-like particles (VLPs) similar to authentic virions in size and shape are assembled, demonstrating that the M and E proteins are the minimal requirements for envelope formation.(4)

Below you will find a selection of our SARS-CoV membrane protein antibodies. Click on the links to see more details.

Product
Clonality
Application
Cat. No.
Quantity
Datasheet
Clonality Polyclonal
Application WB
Cat. No. ABIN199995
Quantity 100 μg
Datasheet Datasheet

Products for nCoV Receptors

Current research indicates that is the key receptor that enables nCoV to enter the cells.(5) Antibodies and kits related to ACE2 and other receptors discussed in the literature are listed below.

Need Help? Call our PhD Customer Support!

  • We will help you to find the right products for your research.
  • We offer reliable antibodies, kits, proteins, lysates for SARS virus research.
  • Contact us via email or phone: (877) 302 8632 (US) or +49 241 95 163 153 (International)

References

Li: "Structure, Function, and Evolution of Coronavirus Spike Proteins." in: Annual review of virology, Vol. 3, Issue 1, pp. 237-261, (2017) (PubMed).

Li, Lin, Wang, Yin, Ren, Zhao, Wen, Zhou, Zhang, Li, Wang, Zhou, Liu, Shao, Lei, Fang, Xu, Liu: "The epitope study on the SARS-CoV nucleocapsid protein." in: Genomics, proteomics & bioinformatics, Vol. 1, Issue 3, pp. 198-206, (2005) (PubMed).

Schoeman, Fielding: "Coronavirus envelope protein: current knowledge." in: Virology journal, Vol. 16, Issue 1, pp. 69, (2019) (PubMed).

de Haan, Smeets, Vernooij, Vennema, Rottier: "Mapping of the coronavirus membrane protein domains involved in interaction with the spike protein." in: Journal of virology, Vol. 73, Issue 9, pp. 7441-52, (1999) (PubMed).

Jia, Look, Shi, Hickey, Pewe, Netland, Farzan, Wohlford-Lenane, Perlman, McCray: "ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia." in: Journal of virology, Vol. 79, Issue 23, pp. 14614-21, (2006) (PubMed).

Cheng, Lau, Woo, Yuen: "Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection." in: Clinical microbiology reviews, Vol. 20, Issue 4, pp. 660-94, (2007) (PubMed).

Rene von der Forst
Rene von der Forst, MSE
Marketing and E-Commerce Manager

Master of Science in engineering. 12+ years of experience in marketing and e-commerce in the life science sector.

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