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BACE1 Proteins

(Beta-secretase 1 (BACE1))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].

23 results

BACE1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7273905
 
BACE1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7273904
 
BACE1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7273906
 
BACE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Catalog No. ABIN7121998
 
BACE1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Catalog No. ABIN1346345
 
BACE1 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Catalog No. ABIN7320444
 
BACE1 Origin: Human Host: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE.
Pubmed 2 references
Catalog No. ABIN2180626
 
BACE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505103
 
BACE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Catalog No. ABIN7575117
 
BACE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Catalog No. ABIN7391801
 
BACE1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC
Catalog No. ABIN7411204
 
BACE1 Origin: Human Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
Catalog No. ABIN7607491
 
BACE1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7391804
 
BACE1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7391807
 
BACE1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7318053
 
BACE1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7318054
 
BACE1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7318055
 
BACE1 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS, EAA Active
Catalog No. ABIN7596290
 
BACE1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Catalog No. ABIN3008460
 
BACE1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2715129
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Enzyme Activity Assay (EAA)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cow
    • Guinea Pig
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Yeast
    • Baculovirus infected Insect Cells
    • Mammalian Cells
    • Wheat germ
  • Binding Specificity
    • AA 22-457
    • AA 170-428
    • AA 181-366
    • AA 190-430
    • AA 22-429
    • AA 22-460
    • AA 22-501
    • AA 46-152
    • Transcript Variant A
  • Conjugate
    • His tag
    • Un-conjugated
    • Fc Tag
    • His tag,GST tag
    • GST tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Supplier
    • antibodies-online
    • CUSABIO
    • ACROBiosystems
    • Abbexa
    • OriGene

Latest Publications for our BACE1 Proteins

Mycroft-West, Devlin, Cooper, Procter, Miller, Fernig, Guerrini, Guimond, Lima, Yates, Skidmore: "Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus." in: Neural regeneration research, Vol. 15, Issue 8, pp. 1546-1553, (2020) (PubMed).

Peters-Libeu, Campagna, Mitsumori, Poksay, Spilman, Sabogal, Bredesen, John: "sAβPPα is a Potent Endogenous Inhibitor of BACE1." in: Journal of Alzheimer's disease : JAD, Vol. 47, Issue 3, pp. 545-55, (2015) (PubMed).

Aliases for BACE1 Proteins

beta-secretase 1 (BACE1) Proteins
beta-site APP cleaving enzyme 1 (Bace1) Proteins
beta-secretase 1 (Bace1) Proteins
beta-site APP-cleaving enzyme 1 (bace1) Proteins
ASP2 Proteins
BACE Proteins
Bace Proteins
BACE1 Proteins
C76936 Proteins
HSPC104 Proteins
MGC145931 Proteins
zgc:77409 Proteins
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