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BICD2 Products

(Bicaudal D Homolog 2 (BICD2))

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This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described. [provided by RefSeq, Jul 2008].

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Featured BICD2 Categories

BICD2 Antibodies

High quality antibodies with extensive validation data.

Recommended BICD2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7165140
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN392178
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6137555
Quantity 100 μL
Datasheet Datasheet

Recommended BICD2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3089939
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136866
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our BICD2 products

Lee, Jung, Oh, Choi, Chae, Kim, Lim, Kim, Lee, Seong, Han: "BICD1 mediates HIF1α nuclear translocation in mesenchymal stem cells during hypoxia adaptation." in: Cell death and differentiation, (2018) (PubMed).

Terenzio, Golding, Russell, Wicher, Rosewell, Spencer-Dene, Ish-Horowicz, Schiavo: "Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors." in: The EMBO journal, Vol. 33, Issue 14, pp. 1582-98, (2014) (PubMed).

Teuling, van Dis, Wulf, Haasdijk, Akhmanova, Hoogenraad, Jaarsma: "A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice." in: Human molecular genetics, Vol. 17, Issue 18, pp. 2849-62, (2008) (PubMed).

Holland, Milne, Garka, Johnson, Willis, Sims, Rauch, Bird, Virca: "Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2." in: The Journal of biological chemistry, Vol. 277, Issue 18, pp. 16229-40, (2002) (PubMed).

Hoogenraad, Akhmanova, Howell, Dortland, De Zeeuw, Willemsen, Visser, Grosveld, Galjart: "Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes." in: The EMBO journal, Vol. 20, Issue 15, pp. 4041-54, (2001) (PubMed).

Synonyms and alternative names related to BICD2

BICD cargo adaptor 2 (BICD2), bicaudal D homolog 2 (Drosophila) (Bicd2), BICD cargo adaptor 2 (Bicd2), BICD cargo adaptor 2 L homeolog (bicd2.L), BICD cargo adaptor 2 (bicd2), zgc:171572 (zgc:171572), 0610027D24Rik, 1110005D12Rik, AA408834, bA526D8.1, BICD2, bicd2, MGC84972, mKIAA0699, SMALED2

Protein level used designations for BICD2

  • bic-D 2
  • coiled-coil protein BICD2
  • cytoskeleton-like bicaudal D protein homolog 2
  • homolog of Drosophila bicaudal D
  • protein bicaudal D homolog 2
  • bicaudal D homolog 2
  • bicaudal D protein
  • bicaudal D homolog 2 (Drosophila)
  • protein bicaudal D homolog 2-like
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