Biglycan Products
(Biglycan (BGN))
Categories
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex. [provided by RefSeq, Nov 2009].
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Featured Biglycan Categories
Biglycan Antibodies
High quality antibodies with extensive validation data.
Biglycan ELISA Kits
Reliable ELISA kits for a wide range of species.
Biglycan Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Biglycan Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IHC (p)
Validations
- (1)
- (7)
Cat. No.
ABIN560056
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7438334
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7436627
Quantity
100 μL
Datasheet
Datasheet
Recommended Biglycan ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (4)
Cat. No.
ABIN6720596
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6954101
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965173
Quantity
96 tests
Datasheet
Datasheet
Recommended Biglycan Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1346652
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7320153
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3085870
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Biglycan products
: "Tenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing." in: Cell death & disease, Vol. 8, Issue 10, pp. e3116, (2018) (PubMed).: "Tumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysregulation of biglycan." in: Scientific reports, Vol. 6, pp. 28039, (2016) (PubMed).
: "An Animal Model of Modic Changes by Embedding Autogenous Nucleus Pulposus inside Subchondral Bone of Lumbar Vertebrae." in: Scientific reports, Vol. 6, pp. 35102, (2016) (PubMed).
: "The Small Leucine-Rich Proteoglycan BGN Accumulates in CADASIL and Binds to NOTCH3." in: Translational stroke research, Vol. 6, Issue 2, pp. 148-55, (2015) (PubMed).
: "Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion." in: Oncoscience, Vol. 1, Issue 10, pp. 634-48, (2015) (PubMed).
: "Serglycin in Quiescent and Proliferating Primary Endothelial Cells." in: PLoS ONE, Vol. 10, Issue 12, pp. e0145584, (2015) (PubMed).
: "The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 731395, (2014) (PubMed).
: "Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells." in: Glycoconjugate journal, Vol. 30, Issue 5, pp. 497-510, (2013) (PubMed).
: "Arguments for an increasing differentiation towards fibrocartilaginous components in midportion Achilles tendinopathy." in: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, Vol. 21, Issue 6, pp. 1459-67, (2013) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
Synonyms and alternative names related to Biglycan
biglycan (BGN), biglycan (Bgn), biglycan L homeolog (bgn.L), biglycan a (bgna), biglycan S homeolog (bgn.S), biglycan (bgn), biglycan b (bgnb), BG, bgn, BGN, BSPG1, DKFZp468I2427, DSPG1, dspg1, PG-S1, pg-s1, PGI, SLRR1A, slrr1a, xbgn, zgc:77123, zgc:91989Protein level used designations for Biglycan
- biglycan proteoglycan
- bone/cartilage proteoglycan I
- bone/cartilage proteoglycan-I
- dermatan sulphate proteoglycan I
- small leucine-rich protein 1A
- PG-S1
- Small proteoglycan I (biglycan), bone (BSPG1) (bone/cartilage proteclycan 1 precursor)
- bone/cartilage proteclycan 1
- leucine-rich PG I
- biglycan
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