BMPR2 Products
(Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
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This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008].
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Featured BMPR2 Categories
BMPR2 Antibodies
High quality antibodies with extensive validation data.
BMPR2 ELISA Kits
Reliable ELISA kits for a wide range of species.
BMPR2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended BMPR2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
- (4)
Cat. No.
ABIN968987
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IHC, ICC
Validations
- (2)
- (4)
Cat. No.
ABIN968988
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (2)
- (4)
Cat. No.
ABIN542871
Quantity
400 μL
Datasheet
Datasheet
Recommended BMPR2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965212
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962060
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954156
Quantity
96 tests
Datasheet
Datasheet
Recommended BMPR2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1346791
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5569816
Quantity
5 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3090276
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our BMPR2 products
: "TGF‑β1 affects the renal cancer miRNome and regulates tumor cells proliferation." in: International journal of molecular medicine, Vol. 49, Issue 4, (2022) (PubMed).: "MicroRNA-155 inhibits the osteogenic differentiation of mesenchymal stem cells induced by BMP9 via downregulation of BMP signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3379-3393, (2018) (PubMed).
: "Baicalein attenuates monocrotaline-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition." in: Life sciences, Vol. 207, pp. 442-450, (2018) (PubMed).
: "BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5." in: PLoS ONE, Vol. 12, Issue 5, pp. e0177188, (2017) (PubMed).
: "Endocytosis contributes to BMP2-induced Smad signalling and neuronal growth." in: Neuroscience letters, Vol. 643, pp. 32-37, (2017) (PubMed).
: "Correlating the Effects of Bone Morphogenic Protein to Secreted Soluble Factors from Fibroblasts and Mesenchymal Stem Cells in Regulating Regenerative Processes In Vitro." in: Tissue engineering. Part A, (2014) (PubMed).
: "BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells." in: Molecular cancer research : MCR, Vol. 12, Issue 2, pp. 283-94, (2014) (PubMed).
: "Epigenetic repression of bone morphogenetic protein receptor II expression in scleroderma." in: Journal of cellular and molecular medicine, Vol. 17, Issue 10, pp. 1291-9, (2014) (PubMed).
: "Roles of miR-1-1 and miR-181c in ventricular septal defects." in: International journal of cardiology, Vol. 168, Issue 2, pp. 1441-6, (2013) (PubMed).
: "Bone morphogenetic protein-9 activates Smad and ERK pathways and supports human osteoclast function and survival in vitro." in: Cellular signalling, Vol. 25, Issue 4, pp. 717-28, (2013) (PubMed).
Synonyms and alternative names related to BMPR2
bone morphogenetic protein receptor type 2 (BMPR2), bone morphogenetic protein receptor, type II b (serine/threonine kinase) (bmpr2b), bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), bone morphogenetic protein receptor type 2 (Bmpr2), 2610024H22Rik, AL117858, AW546137, BB189135, BMP-2, BMPR-2, BMPR-II, Bmpr-II, BMPR3, BMPRII, bmprii, BMR2, BRK-3, Gm20272, PPH1, T-ALKProtein level used designations for BMPR2
- bone morphogenetic protein receptor type II
- bone morphogenetic protein receptor type-2
- bone morphogenetic protein receptor type II b
- BMP type II receptor
- BMP type-2 receptor
- BMPR-2
- type II activin receptor-like kinase
- type II receptor for bone morphogenetic protein-4
- bone morphogenic protein receptor, type II (serine/threonine kinase)
- bone morphogenic protein receptor type 2
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