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anti-Human CEBPA Antibodies:
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Human Monoclonal CEBPA Primary Antibody for FACS, ICC - ABIN269606
Ferrari-Amorotti, Keeshan, Zattoni, Guerzoni, Iotti, Cattelani, Donato, Calabretta: Leukemogenesis induced by wild-type and STI571-resistant BCR/ABL is potently suppressed by C/EBPalpha. in Blood 2006
Show all 4 Pubmed References
Cow (Bovine) Polyclonal CEBPA Primary Antibody for IHC, WB - ABIN2787465
Singh, Trivedi, Behre: C/EBPalpha S248A mutation reduces granulocytic differentiation in human leukemic K562 cells. in Biochemical and biophysical research communications 2008
Show all 3 Pubmed References
Human Monoclonal CEBPA Primary Antibody for FACS, ELISA - ABIN969507
Geest, Buitenhuis, Vellenga, Coffer: Ectopic expression of C/EBPalpha and ID1 is sufficient to restore defective neutrophil development in low-risk myelodysplasia. in Haematologica 2009
Human Monoclonal CEBPA Primary Antibody for ICC, FACS - ABIN969048
Jin, Zhang, Yan, Liu, Wang, Ge, Zhai: C/EBPalpha regulates SIRT1 expression during adipogenesis. in Cell research 2010
Data suggest that up-regulation of NPY (show NPY Antibodies) inhibits proliferation of adipose-derived stem cells while promoting adipogenesis and up-regulating expression of white adipocyte biomarkers PPARG (show PPARG Antibodies), CEBPA, CIDEC (show CIDEC Antibodies), and RIP140 (show NRIP1 Antibodies). (NPY (show NPY Antibodies) = neuropeptide Y (show NPY Antibodies); PPARG (show PPARG Antibodies) = peroxisome proliferator activated receptor gamma (show PPARG Antibodies); CIDEC (show CIDEC Antibodies) = cell death-inducing DFFA-like effector C (show CIDEC Antibodies); RIP140 (show NRIP1 Antibodies) = nuclear receptor interacting protein 1 (show NRIP1 Antibodies))
Study identified for the first time that HNF4alpha (show HNF4A Antibodies) and C/EBPalpha are important transcriptional regulators for FBP1 (show FBP1 Antibodies) expression in human hepatoma HepG2 cells.
The presence of biallelic CEBPA mutations is a favourable prognostic feature in acute myeloid leukaemia.
C/EBP-alpha mediates anti-inflammatory effects in podocytes
proteogenomics profiling study reveals that an activation of C/EBPalpha, along with the upregulation of its lipogenesis targets, accounts for lipid storage and acts as a hallmark of ARVC ( Arrhythmogenic right ventricular cardiomyopathy)
Taken together, the authors propose that the miR (show MLXIP Antibodies)-939-Jmjd3 (show Kdm6b Antibodies) axis perturbs the accessibility of hepatitis B virus enhancer II/core promoter (En II) promoter to essential nuclear factors (C/EBPalpha and SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) complex) therefore leading to compromised viral RNA synthesis and hence restricted viral multiplication.
EBPA and RUNX1 (show RUNX1 Antibodies) are expressed at higher levels in patients with acute myeloid leukemia (show BCL11A Antibodies) in comparison to healthy subjects
Integration of WGS-based fine-mapping and complementary epigenomic datasets provided evidence for causal mechanisms at several loci, including at a previously undiscovered basophil count-associated locus near the master hematopoietic transcription factor CEBPA The fine-mapped variant at this basophil count association near CEBPA overlapped an enhancer active in common myeloid progenitors and influenced its activity.
in our study on a large cohort of CEBPAmut AML (show RUNX1 Antibodies) patients, we found a high coincidence of GATA2mut, in particular within the subgroup of patients with CEBPAbi mutations
a decision analysis comparing allo-HCT vs chemotherapy in first complete remission for patients with cytogenetically intermediate-risk acute myeloid leukemia (show BCL11A Antibodies), depending on the presence or absence of FLT3 (show FLT3 Antibodies)-ITD), NPM1 (show NPM1 Antibodies), and CEBPA mutations showed that allo-HCT was a favored postremission strategy in patients with FLT3 (show FLT3 Antibodies)-ITD, and chemotherapy was favored in patients with biallelic CEBPA mutations.
under nutrient-limiting conditions that stimulate ATF4 (show ATF4 Antibodies) activity, TRIB3 (show TRIB3 Antibodies) is implicated in the regulation of metabolic adaptation by restraining the transcription of Fgf21 (show FGF21 Antibodies).
the extracts dramatically attenuated the levels of adipogenic transcriptional factors, including CCAAT enhancer-binding protein alpha (C/EBPa), CCAAT enhancer-binding protein beta (C/EBPb (show CEBPB Antibodies)), and gamma receptors by peroxisome proliferators (PPARg (show PPARG Antibodies)), during adipogenesis
shown that ectopic miR (show MLXIP Antibodies)-155 expression and loss of C/EBPA expression in myeloid progenitor cells cooperate in transformation of HSPCs toward AML (show RUNX1 Antibodies) in the absence of FLT3 (show FLT3 Antibodies)-ITD
The Bach2 (show BACH2 Antibodies)-C/EBPbeta (show CEBPB Antibodies) gene regulatory network pathway tunes multipotent progenitor commitment to myeloid and lymphoid lineages both under normal conditions and after infection.
Data demonstrate the importance of a controlled balance between C/EBPalpha and miR (show MLXIP Antibodies)-182 for the maintenance of healthy granulopoiesis.
Functional characterization of C/EBPa and C/EBPb (show CEBPB Antibodies) proteomes suggests they can regulate novel pathways.
results indicate that JMJD2B (show KDM4B Antibodies) regulates PPARgamma (show PPARG Antibodies) and C/EBPalpha during adipogenesis
A single +42-kb enhancer is essential for CEBPA expression in myeloid cells only.
these data indicate that CycC (show CCNC Antibodies) activates adipogenesis in part by stimulating the transcriptional activity of C/EBPalpha.
C/ebpalpha plays a role in liver growth regulation via the p53 (show TP53 Antibodies) pathway.
Dnmt1 (show DNMT1 Antibodies) is required for hematopoietic stem and progenitor cells maintenance via cebpa regulation during definitive hematopoiesis in zebrafish
Data suggest that upregulation of 10-formyltetrahydrofolate dehydrogenase (FDH (show ALDH1L1 Antibodies)) involving CEBPalpha helps relieve embryonic oxidative stress induced (show SQSTM1 Antibodies) by ethanol exposure.
Bmi1 (show BMI1 Antibodies) acts immediately downstream of CCAAT enhancer binding protein-alpha to regulate the survival and self-renewal of hematopoietic stem cells and contribute to the erythropoietic dysplasia.
Results provide first evidence that sumoylation of Cebp-alpha (via SUMO1 (show SUMO1 Antibodies), SUMO2 (show SUMO2 Antibodies), and SUMO3 (show SUMO3 Antibodies)) might contribute to cell fate decision of myelo-erythroid progenitor cells in intermediate cell mass during primitive [extramedullary] hematopoiesis.
An evolutionarily conserved PTEN-C/EBPalpha-CTNNA1 (show CTNNA1 Antibodies) axis controls myeloid development and transformation.
a C/EBP recognition sequence in the proximal promoter region of C/EBPalpha is essential for IL-6 (show IL6 Antibodies)-mediated repression
These results suggest that the CEBPA gene is a strong candidate gene that affects carcass traits in Qinchuan cattle.
Expressions of C-EBPalpha and myostatin (show MSTN Antibodies) in muscles were higher in the concentrate-fed group than in the grass hay (show GTF2H5 Antibodies)-fed group.
C/EBPalpha is an essential regulatory factor for perilipin5 transcription and suggest that fasting stimulates perilipin5 transcription through influencing C/EBPalpha expression.
The differential expression of specific CEBPA/B isoforms observed in maturing follicles and CL may contribute to changes in follicular cell differentiation and increasing steroidogenic capacity.
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
CCAAT/enhancer-binding protein alpha
, C/EBP alpha
, CAAT/enhancer-binding protein DNA-binding protein
, CAAT/enhancer-binding protein, DNA-binding protein
, CCAAT/enhancer binding protein, alpha
, c/EBP alpha
, CCAAT/enhancer binding protein alpha