C-Type Lectin Domain Family 2, Member I (CLEC2I) (AA 1-217) protein (His tag)
custom-made
CLEC2I
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target See all C-Type Lectin Domain Family 2, Member I (CLEC2I) products
- C-Type Lectin Domain Family 2, Member I (CLEC2I)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-217
- Origin
- Mouse
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- His tag
- Purpose
- Predefined custom protein recombinant Clec2i Protein expressed in mammalian cells.
- Sequence
- MPDCLETGEK LFVHNMNAQC VQKPEEGNGP LGTGGKIVQG KCFRIISTVS PVKLYCCYGV IMVLTVAVIA LSVALSTKKT EQIIINKTYA ACSKNWTGVG NKCFYFSGYP RNWTFAQAFC MAQEAQLARF DNEEELIFLK RFKGDFDCWI GLHRESSEHP WKWTNNTEYN NMNPILGVGR YAYLSSDRIS SSRSYINRMW ICSKLNNYNL HCQTPPV Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- C-Type Lectin Domain Family 2, Member I (CLEC2I)
- Alternative Name
- Clec2i
- Background
- C-type lectin domain family 2 member I (C-type lectin-related protein DCL1) (C-type lectin-related protein G) (Clr-g) (Lymphoid-derived C-type lectin-1) (LCL-1) (Osteoclast inhibitory lectin-related protein 2) (Ocil-related protein 2),FUNCTION: Inhibits osteoclast formation. Receptor for KLRB1F. Enhances T-cell activation. Plays a role in splenocyte activation, T-cell responses and IL-2 production. {ECO:0000269|PubMed:12374791, ECO:0000269|PubMed:15963483}.
- Molecular Weight
- 24.7 kDa
- UniProt
- Q9WVF9
- AlphaFold
- Q9WVF9
- Pathways
- Regulation of Actin Filament Polymerization
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