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CENPB Products

(Centromere Protein B (CENPB))

Categories

This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq, Jul 2008].

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Featured CENPB Categories

CENPB Antibodies

High quality antibodies with extensive validation data.

CENPB ELISA Kits

Reliable ELISA kits for a wide range of species.

CENPB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CENPB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN514341
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN514342
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC, IP
Validations
  • (2)
Cat. No. ABIN6971525
Quantity 100 μL
Datasheet Datasheet

Recommended CENPB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965626
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1114052
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5564601
Quantity 96 tests
Datasheet Datasheet

Recommended CENPB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3091026
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133534
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393271
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CENPB products

Fachinetti, Folco, Nechemia-Arbely, Valente, Nguyen, Wong, Zhu, Holland, Desai, Jansen, Cleveland: "A two-step mechanism for epigenetic specification of centromere identity and function." in: Nature cell biology, Vol. 15, Issue 9, pp. 1056-66, (2013) (PubMed).

Synonyms and alternative names related to CENPB

centromere protein B (CENPB), centromere protein B (Cenpb), centromere protein B, 80kDa (Cenpb), CENP-B, CENPB

Protein level used designations for CENPB

  • CENP-B
  • centromere autoantigen B
  • major centromere autoantigen B
  • CENP-B protein
  • centromere protein B
  • Major centromere autoantigen B
  • centromere autoantigen protein B
  • centromere protein B, 80kDa
  • LOW QUALITY PROTEIN: major centromere autoantigen B
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