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CENPE Products

(Centromere Protein E, 312kDa (CENPE))
Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation. [provided by RefSeq, Jul 2008].

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Featured CENPE Categories

CENPE Antibodies

High quality antibodies with extensive validation data.

CENPE ELISA Kits

Reliable ELISA kits for a wide range of species.

CENPE Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CENPE Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7190211
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IP, IF, ICC, FACS
Validations
  • (10)
  • (1)
Cat. No. ABIN108562
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7243160
Quantity 200 μL
Datasheet Datasheet

Recommended CENPE ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954555
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN511321
Quantity 96 tests
Datasheet Datasheet
Reactivity Guinea Pig
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN776522
Quantity 96 tests
Datasheet Datasheet

Recommended CENPE Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349106
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405588
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406053
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CENPE products

Hu, Coughlin, Mitchison: "Midbody assembly and its regulation during cytokinesis." in: Molecular biology of the cell, Vol. 23, Issue 6, pp. 1024-34, (2012) (PubMed).

Serio, Margaria, Jensen, Oldani, Bartek, Bussolino, Lanzetti: "Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochores." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 42, pp. 17337-42, (2011) (PubMed).

Kim, Holland, Lan, Cleveland: "Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E." in: Cell, Vol. 142, Issue 3, pp. 444-55, (2010) (PubMed).

Stimpson, Song, Jauch, Holtgreve-Grez, Hayden, Bridger, Sullivan: "Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes." in: PLoS genetics, Vol. 6, Issue 8, (2010) (PubMed).

Townsend, Mason, Blackford, Miller, Chapman, Sedgwick, Barone, Turnell, Stewart: "Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression." in: The Journal of biological chemistry, Vol. 284, Issue 49, pp. 33939-48, (2009) (PubMed).

Cheng, Hsiao, Lin, Yu, Hsu, Chang, Lee, Huang, Howng, Hong: "Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrin." in: The Journal of biological chemistry, Vol. 283, Issue 4, pp. 2454-64, (2008) (PubMed).

Díaz-Martínez, Giménez-Abián, Azuma, Guacci, Giménez-Martín, Lanier, Clarke: "PIASgamma is required for faithful chromosome segregation in human cells." in: PLoS ONE, Vol. 1, pp. e53, (2007) (PubMed).

Schafer-Hales, Iaconelli, Snyder, Prussia, Nettles, El-Naggar, Khuri, Giannakakou, Marcus: "Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function." in: Molecular cancer therapeutics, Vol. 6, Issue 4, pp. 1317-28, (2007) (PubMed).

Chang, Coughlin, Mitchison: "Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function." in: Nature cell biology, Vol. 7, Issue 11, pp. 1133-9, (2005) (PubMed).

Yen, Compton, Wise, Zinkowski, Brinkley, Earnshaw, Cleveland: "CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase." in: The EMBO journal, Vol. 10, Issue 5, pp. 1245-54, (1991) (PubMed).

Synonyms and alternative names related to CENPE

centromere protein E (CENPE), centromere protein E (Cenpe), centromere protein E, 312kDa (CENPE), centromere protein E (cenpe), 312kDa, AU019344, BC049989, C530022J18, CENP-E, cenp-E, CENPE, KIF10, Kif10, kif10, PPP1R61, wu:fc06a10, XCENP-E, zgc:152925

Protein level used designations for CENPE

  • Centromere autoantigen E (312kD)
  • centromere-associated protein E
  • kinesin family member 10
  • kinesin-related protein CENPE
  • protein phosphatase 1, regulatory subunit 61
  • N-7 kinesin
  • centromere autoantigen E
  • centromeric protein E
  • kinesin 10
  • kinesin superfamily protein 10
  • motor domain of KIF10
  • centromere protein E, 312kDa
  • centromere protein E - 312kD
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