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CERK Products

(Ceramide Kinase (CERK))

Categories

CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008].

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Featured CERK Categories

CERK Antibodies

High quality antibodies with extensive validation data.

CERK ELISA Kits

Reliable ELISA kits for a wide range of species.

CERK Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CERK Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, WB, IF
Validations
  • (4)
Cat. No. ABIN7147455
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (3)
  • (2)
Cat. No. ABIN391126
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7236232
Quantity 200 μL
Datasheet Datasheet

Recommended CERK ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6965628
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954557
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5592930
Quantity 96 tests
Datasheet Datasheet

Recommended CERK Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349170
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409389
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3091030
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CERK products

Dória, Ribeiro, Wang, Cotrim, Domingues, Williams, Domingues, Helguero: "Fatty acid and phospholipid biosynthetic pathways are regulated throughout mammary epithelial cell differentiation and correlate to breast cancer survival." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 10, pp. 4247-64, (2014) (PubMed).

Murakami, Ito, Hagiwara, Yoshida, Sobue, Ichihara, Takagi, Kojima, Tanaka, Tamiya-Koizumi, Kyogashima, Suzuki, Banno, Nozawa, Murate: "ATRA inhibits ceramide kinase transcription in a human neuroblastoma cell line, SH-SY5Y cells: the role of COUP-TFI." in: Journal of neurochemistry, Vol. 112, Issue 2, pp. 511-20, (2010) (PubMed).

Yang, Gagarin, St Laurent, Hammell, Toma, Hu, Iwasa, McCaffrey: "Cardiovascular inflammation and lesion cell apoptosis: a novel connection via the interferon-inducible immunoproteasome." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 29, Issue 8, pp. 1213-9, (2009) (PubMed).

Hinkovska-Galcheva, Clark, VanWay, Huang, Hiraoka, Abe, Borofsky, Kunkel, Shanley, Shayman, Lanni, Petty, Boxer: "Ceramide kinase promotes Ca2+ signaling near IgG-opsonized targets and enhances phagolysosomal fusion in COS-1 cells." in: Journal of lipid research, Vol. 49, Issue 3, pp. 531-42, (2008) (PubMed).

Lamour, Chalfant: "Ceramide-1-phosphate: the "missing" link in eicosanoid biosynthesis and inflammation." in: Molecular interventions, Vol. 5, Issue 6, pp. 358-67, (2006) (PubMed).

Van Overloop, Gijsbers, Van Veldhoven: "Further characterization of mammalian ceramide kinase: substrate delivery and (stereo)specificity, tissue distribution, and subcellular localization studies." in: Journal of lipid research, Vol. 47, Issue 2, pp. 268-83, (2006) (PubMed).

Kim, Mitsutake, Kato, Igarashi: "The leucine 10 residue in the pleckstrin homology domain of ceramide kinase is crucial for its catalytic activity." in: FEBS letters, Vol. 579, Issue 20, pp. 4383-8, (2005) (PubMed).

Wijesinghe, Massiello, Subramanian, Szulc, Bielawska, Chalfant: "Substrate specificity of human ceramide kinase." in: Journal of lipid research, Vol. 46, Issue 12, pp. 2706-16, (2005) (PubMed).

Mitsutake, Kim, Inagaki, Kato, Yamashita, Igarashi: "Ceramide kinase is a mediator of calcium-dependent degranulation in mast cells." in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17570-7, (2004) (PubMed).

Pettus, Bielawska, Spiegel, Roddy, Hannun, Chalfant: "Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38206-13, (2003) (PubMed).

Synonyms and alternative names related to CERK

ceramide kinase (Cerk), ceramide kinase (CERK), ceramide kinase (cerk), ceramide kinase S homeolog (cerk.S), ceramide kinase (CpipJ_CPIJ003342), ceramide kinase (LOAG_11245), Ceramide kinase (Cerk), ceramide kinase (LOC5579301), Ceramide kinase (Bm1_50005), AI848610, CERK, CG16708, D330016D08Rik, dA59H18.2, dA59H18.3, DCERK, Dcerk, dcerk, Dmel\\CG16708, hCERK, LK4, MGC81777, mKIAA1646, si:ch211-162i19.1

Protein level used designations for CERK

  • acylsphingosine kinase
  • mCERK
  • lipid kinase 4
  • lipid kinase LK4
  • ceramide kinase
  • CG16708-PA
  • CG16708-PB
  • Cerk-PA
  • Cerk-PB
  • Ceramide kinase
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