Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich element (ARE)-containing mRNAs by binding to themm and inhibiting their deadenylation. Essential for embryonic gastrulation and neural development, acting to maintain the expression of a set of adhesion molecules, and cell movement during embryogenesis. Required for pronephros development (By similarity).
custom-made
CIRBP
Origin: Human
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
CIRBP
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Latest Publications for our Cold Inducible RNA Binding Protein Proteins
Qiang, Yang, Wu, Zhou, Jacob, Dong, Kuncewitch, Ji, Yang, Wang, Fujita, Nicastro, Coppa, Tracey, Wang: "Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis." in: Nature medicine, Vol. 19, Issue 11, pp. 1489-95, (2013) (PubMed).
Mangé, Lacombe, Bascoul-Mollevi, Jarlier, Lamy, Rouanet, Maudelonde, Solassol: "Serum autoantibody signature of ductal carcinoma in situ progression to invasive breast cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 7, pp. 1992-2000, (2012) (PubMed).
Aliases for Cold Inducible RNA Binding Protein Proteins
cold inducible RNA binding protein (CIRBP) Proteins cold-inducible RNA-binding protein (EDI_107320) Proteins cold inducible RNA binding protein (Cirbp) Proteins cold inducible RNA binding protein S homeolog (cirbp.S) Proteins cold inducible RNA binding protein L homeolog (cirbp.L) Proteins cold inducible RNA binding protein (cirbp) Proteins cold inducible RNA binding protein b (cirbpb) Proteins A18 hnRNP Proteins APBP-1 Proteins cirbp Proteins CIRBP Proteins cirbp-a Proteins cirbp-b Proteins cirbp2 Proteins CIRP Proteins Cirp Proteins cirp Proteins cirp-1 Proteins cirp1 Proteins cirp2 Proteins R74941 Proteins Xcirp Proteins XCIRP Proteins XCIRP-1 Proteins xcirp2 Proteins zgc:136559 Proteins