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COMP Proteins

(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].

21 results

COMP Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7583901
$2,211.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 72 Business Days
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunogen (Imm)
    • Positive Control (PC)
    • ELISA
    • Affinity Measurement (AM)
    • Antibody Production (AbP)
    • Immunoassay (IA)
    • Immunoprecipitation (IP)
    • Screening Assay (ScA)
    • Standard (STD)
    • Antibody Drug Assay (ADA)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Bacteria
    • Yeast
  • Binding Specificity
    • AA 123-240
    • AA 21-757
    • AA 20-755
    • AA 22-240
    • AA 235-423
    • AA 317-455
    • AA 35-179
    • AA 35-423
    • AA 40-180
    • AA 544-757
    • AA 554-753
    • AA 577-755
    • C-Term
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag,His tag
    • GST-His-Tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
    • Biologically Inactive
  • Supplier
    • antibodies-online
    • ProteoGenix
    • Abbexa
    • CUSABIO
    • ITSI-Biosciences
    • OriGene

Latest Publications for our COMP Proteins

Wang, Chen, Xiang, Wu, Tang, Ma, Zhang: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." in: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).

Spitznagel, Nitsche, Paulsson, Maurer, Zaucke: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." in: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).

Aliases for COMP Proteins

cartilage oligomeric matrix protein (COMP) Proteins
cartilage oligomeric matrix protein (sce3551) Proteins
cartilage oligomeric matrix protein (CJA_1292) Proteins
cartilage oligomeric matrix protein (Comp) Proteins
COMP Proteins
EDM1 Proteins
EPD1 Proteins
MED Proteins
PSACH Proteins
THBS5 Proteins
TSP5 Proteins
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