Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CRTC1 Products

(CREB Regulated Transcription Coactivator 1 (CRTC1))
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells (By similarity). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons.

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured CRTC1 Categories

CRTC1 Antibodies

High quality antibodies with extensive validation data.

CRTC1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CRTC1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CRTC1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Chicken, Human
Application WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
  • (4)
Cat. No. ABIN746558
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP, FACS, ICC
Validations
  • (4)
Cat. No. ABIN6241239
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, ICC
Validations
  • (3)
  • (3)
Cat. No. ABIN969066
Quantity 100 μL
Datasheet Datasheet

Recommended CRTC1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955105
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN427062
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6203034
Quantity 96 tests
Datasheet Datasheet

Recommended CRTC1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350404
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420138
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3091973
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CRTC1 products

Heinrich, Böer, Tzvetkov, Oetjen, Knepel: "Stimulation by lithium of the interaction between the transcription factor CREB and its co-activator TORC." in: Bioscience reports, Vol. 29, Issue 2, pp. 77-87, (2009) (PubMed).

Fehr, Röser, Belge, Löning, Bullerdiek: "A closer look at Warthin tumors and the t(11;19)." in: Cancer genetics and cytogenetics, Vol. 180, Issue 2, pp. 135-9, (2008) (PubMed).

Winnes, Mölne, Suurküla, Andrén, Persson, Enlund, Stenman: "Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas." in: Genes, chromosomes & cancer, Vol. 46, Issue 6, pp. 559-63, (2007) (PubMed).

Tonon, Modi, Wu, Kubo, Coxon, Komiya, ONeil, Stover, El-Naggar, Griffin, Kirsch, Kaye: "t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway." in: Nature genetics, Vol. 33, Issue 2, pp. 208-13, (2003) (PubMed).

Synonyms and alternative names related to CRTC1

CREB regulated transcription coactivator 1 (CRTC1), CREB regulated transcription coactivator 1 (Crtc1), CREB regulated transcription coactivator 1 (crtc1), CREB regulated transcription coactivator 1b (crtc1b), AI413414, CRTC1, crtc1, fc68c05, MECT1, Mect1, mKIAA0616, pde4cb, R74955, si:ch211-255d18.1, si:ch211-255d18.8, TORC-1, TORC1, WAMTP1, wu:fc68c05

Protein level used designations for CRTC1

  • CREB-regulated transcription coactivator 1
  • mucoepidermoid carcinoma translocated protein 1
  • transducer of regulated cAMP response element-binding protein (CREB) 1
  • TORC-1
  • mucoepidermoid carcinoma translocated 1
  • mucoepidermoid carcinoma translocated protein 1 homolog
  • transducer of CREB protein 1
  • transducer of regulated cAMP response element-binding protein 1
  • CREB regulated transcription coactivator 1
  • CREB-regulated transcription coactivator 1-like
  • CH211-255D18.10
  • CH211-255D18.9
  • CREB regulated transcription coactivator 1b
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4C
  • phosphodiesterase 4C, cAMP-specific b
  • zfTorc1
You are here:
Support