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DDX5 Products

(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

Categories

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. This gene consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified. [provided by RefSeq, Jul 2008].

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Featured DDX5 Categories

DDX5 Antibodies

High quality antibodies with extensive validation data.

DDX5 ELISA Kits

Reliable ELISA kits for a wide range of species.

DDX5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DDX5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Monkey, Mouse
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (6)
Cat. No. ABIN5542510
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (8)
Cat. No. ABIN6139505
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN185199
Quantity 100 μg
Datasheet Datasheet

Recommended DDX5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955291
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1773417
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774641
Quantity 96 tests
Datasheet Datasheet

Recommended DDX5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
  • (1)
Cat. No. ABIN2719286
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7081055
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135443
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DDX5 products

Sun, Wang, Lin, Zhao, Zhang, Yi, Sun, Chen, Jin: "Proteome analysis of Duck Tembusu virus (DTMUV)-infected BHK-21 cells." in: Proteomics, Vol. 17, Issue 12, (2017) (PubMed).

Taniguchi, Iizumi, Watanabe, Masuda, Morita, Aono, Toriyama, Oishi, Goi, Sakai: "Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer." in: Cell death & disease, Vol. 7, pp. e2211, (2016) (PubMed).

Muller, Hammond, Rio, Lee: "An Efficient Method for Electroporation of Small Interfering RNAs into ENCODE Project Tier 1 GM12878 and K562 Cell Lines." in: Journal of biomolecular techniques : JBT, Vol. 26, Issue 4, pp. 142-9, (2015) (PubMed).

Kost, Yang, Li, Zhang, Liu, Kim, Ahn, Lee, Liu: "A Novel Anti-Cancer Agent, 1-(3,5-Dimethoxyphenyl)-4-[(6-Fluoro-2-Methoxyquinoxalin-3-yl)Aminocarbonyl] Piperazine (RX-5902), Interferes With β-Catenin Function Through Y593 Phospho-p68 RNA Helicase." in: Journal of cellular biochemistry, Vol. 116, Issue 8, pp. 1595-601, (2015) (PubMed).

Huang, Chen, Wu, Huang, He, Tang, Wang, Wang: "The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 4901-13, (2015) (PubMed).

Lorgeoux, Pan, Le Duff, Liang: "DDX17 promotes the production of infectious HIV-1 particles through modulating viral RNA packaging and translation frameshift." in: Virology, Vol. 443, Issue 2, pp. 384-92, (2013) (PubMed).

Naji, Ambrus, Cimerman?i?, Reyes, Johnson, Filbrandt, Huber, Vesely, Krogan, Yates, Saphire, Gerace: "Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 4, pp. M111.015313, (2012) (PubMed).

Saporita, Chang, Winkeler, Apicelli, Kladney, Wang, Townsend, Michel, Weber: "RNA helicase DDX5 is a p53-independent target of ARF that participates in ribosome biogenesis." in: Cancer research, Vol. 71, Issue 21, pp. 6708-17, (2011) (PubMed).

Guo, Hong, Loke, Yea, Lim, Lee, Mann, Walsh, Sninsky, Friedman: "A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5428-37, (2010) (PubMed).

Daub, Olsen, Bairlein, Gnad, Oppermann, Körner, Greff, Kéri, Stemmann, Mann: "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." in: Molecular cell, Vol. 31, Issue 3, pp. 438-48, (2008) (PubMed).

Synonyms and alternative names related to DDX5

DEAD-box helicase 5 (DDX5), DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 (Ddx5), DEAD-box helicase 5 (Ddx5), DEAD (Asp-Glu-Ala-Asp) box helicase 5 (ddx5), DEAD-box helicase 5 (ddx5), DEAD-box helicase 5 L homeolog (ddx5.L), 2600009A06Rik, ddx5, G17P1, HLR1, Hlr1, HUMP68, p68, wu:fa56a07, wu:fb11e01, wu:fb16c10, wu:fb53b05

Protein level used designations for DDX5

  • ATP-dependent RNA helicase DDX5
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
  • DEAD box protein 5
  • DEAD box-5
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD)
  • RNA helicase p68
  • probable ATP-dependent RNA helicase DDX5
  • D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 5
  • DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 5
  • DEAD box RNA helicase DEAD1
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5
  • mDEAD1
  • p68 RNA helicase
  • ddx5 gene protein
  • PCR product with interspecies-compatible primers
  • putative ATP-dependent RNA helicase DDX5
  • DEAD (Asp-Glu-Ala-Asp) box helicase 5
  • DEAD-box helicase 5 L homeolog
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