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Desmoglein 3 Products

(Desmoglein 3 (DSG3))
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq, Jul 2008].

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Featured Desmoglein 3 Categories

Desmoglein 3 Antibodies

High quality antibodies with extensive validation data.

Desmoglein 3 ELISA Kits

Reliable ELISA kits for a wide range of species.

Desmoglein 3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Desmoglein 3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (7)
Cat. No. ABIN2682987
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (4)
Cat. No. ABIN6939268
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (3)
Cat. No. ABIN7431797
Quantity 100 μL
Datasheet Datasheet

Recommended Desmoglein 3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966345
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955368
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4882672
Quantity 96 tests
Datasheet Datasheet

Recommended Desmoglein 3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274501
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274503
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (2)
Cat. No. ABIN3079094
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Desmoglein 3 products

Sumitomo, Mori, Nakamura, Honda-Ogawa, Nakagawa, Yamaguchi, Matsue, Terao, Nakata, Kawabata: "Streptococcal Cysteine Protease-Mediated Cleavage of Desmogleins Is Involved in the Pathogenesis of Cutaneous Infection." in: Frontiers in cellular and infection microbiology, Vol. 8, pp. 10, (2019) (PubMed).

Walter, Vielmuth, Rotkopf, Sárdy, Horváth, Goebeler, Schmidt, Eming, Hertl, Spindler, Waschke: "Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus." in: Scientific reports, Vol. 7, Issue 1, pp. 3579, (2017) (PubMed).

Roden, Yi, Cassivi, Jenkins, Garces, Aubry: "Clinicopathological features of thymic carcinomas and the impact of histopathological agreement on prognostical studies." in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 43, Issue 6, pp. 1131-9, (2013) (PubMed).

Griffin, Wriston, Peters, Lehman: "Decreased expression of intercellular adhesion molecules in acantholytic squamous cell carcinoma compared with invasive well-differentiated squamous cell carcinoma of the skin." in: American journal of clinical pathology, Vol. 139, Issue 4, pp. 442-7, (2013) (PubMed).

Tsang, Liu, Teh, Wheeler, Grose, Hart, Garrod, Fortune, Wan: "Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src." in: PLoS ONE, Vol. 5, Issue 12, pp. e14211, (2010) (PubMed).

Mahoney, Hu, Brennan, Bazzi, Christiano, Wahl: "Delineation of diversified desmoglein distribution in stratified squamous epithelia: implications in diseases." in: Experimental dermatology, Vol. 15, Issue 2, pp. 101-9, (2006) (PubMed).

Lucchese, Mittelman, Lin, Kanduc, Sinha: "Epitope definition by proteomic similarity analysis: identification of the linear determinant of the anti-Dsg3 MAb 5H10." in: Journal of translational medicine, Vol. 2, Issue 1, pp. 43, (2005) (PubMed).

Wu, Stanley, Cotsarelis: "Desmoglein isotype expression in the hair follicle and its cysts correlates with type of keratinization and degree of differentiation." in: The Journal of investigative dermatology, Vol. 120, Issue 6, pp. 1052-7, (2003) (PubMed).

Wahl: "Generation of monoclonal antibodies specific for desmoglein family members." in: Hybridoma and hybridomics, Vol. 21, Issue 1, pp. 37-44, (2002) (PubMed).

Weiske, Schöneberg, Schröder, Hatzfeld, Tauber, Huber: "The fate of desmosomal proteins in apoptotic cells." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 41175-81, (2001) (PubMed).

Synonyms and alternative names related to Desmoglein 3

desmoglein 3 (DSG3), desmoglein 3 (Dsg3), bal, balding, CDHF6, DSG3, PVA

Protein level used designations for Desmoglein 3

  • desmoglein 3 (pemphigus vulgaris antigen)
  • desmoglein-3
  • 130 kDa pemphigus vulgaris antigen
  • 130-kD pemphigus vulgaris antigen
  • cadherin family member 6
  • pemphigus vulgaris antigen
  • 130 kDa pemphigus vulgaris antigen homolog
  • desmoglein 3 preprotein
  • desmoglein 3
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