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Human Monoclonal MCM7 Primary Antibody for IF, IHC (p) - ABIN561764
Köhler, Kreuter, Rozynkowski, Rahmel, Uhl, Tannapfel, Schmidt, Meier: Validation of different replication markers for the detection of beta-cell proliferation in human pancreatic tissue. in Regulatory peptides 2010
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Human Polyclonal MCM7 Primary Antibody for ChIP, ICC - ABIN441356
Hubbi, Luo, Baek, Semenza: MCM proteins are negative regulators of hypoxia-inducible factor 1. in Molecular cell 2011
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Human Polyclonal MCM7 Primary Antibody for PLA, WB - ABIN151719
Nash, Chen, Muzyczka: Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins. in Journal of virology 2008
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Human Polyclonal MCM7 Primary Antibody for IP, WB - ABIN440771
Panneerselvam, Pickering, Han, Li, Zheng, Zhang, Zhang, Fei: Basal level of FANCD2 monoubiquitination is required for the maintenance of a sufficient number of licensed-replication origins to fire at a normal rate. in Oncotarget 2014
Human Monoclonal MCM7 Primary Antibody for FACS, IF - ABIN5583309
Koonin: A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication. in Nucleic acids research 1993
Human Polyclonal MCM7 Primary Antibody for IF, IP - ABIN2452047
Fujita, Kiyono, Hayashi, Ishibashi: hCDC47, a human member of the MCM family. Dissociation of the nucleus-bound form during S phase. in The Journal of biological chemistry 1996
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CDT1 (show CDT1 Antibodies), MCM7, and NUDT1 (show NUDT1 Antibodies) were shown to be up-regulated in hepatocellular carcinoma tissues and provide a more accurate diagnosis than alpha-fetal protein alone.
High expression of MCM-7 was reduced in BVP-treated cancer cells.
Data indicate that RACK1 (show GNB2L1 Antibodies) increases interactions between Akt (show AKT1 Antibodies) and MCM7 and promotes Akt (show AKT1 Antibodies)-dependent MCM7 phosphorylation, which in turn increases MCM7 binding to chromatin and miniature chromosome maintenance (MCM) complex formation.
our findings suggested that MCM7 promoted tumor cell proliferation, colony formation and migration of ESCC cells via activating AKT1 (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway
Results proved that MCM7 proliferative index is a better method for identifying patients with risk of recurrence in patients surgically resected for meningiomas compared with the traditional methods used in the current clinical practice.
MCM7-cyclin D1 (show CCND1 Antibodies) pathway may participate in cancer progression.
The MCM7 directly binds to the centrosomal linker protein (show LAT Antibodies) Cep68 in vitro and complexes with Cep68 and VHL (show VHL Antibodies) in vivo.
The results clearly demonstrate 7q21-22 amplification, MCM7, and its intronic miR (show MLXIP Antibodies)-25 are the major molecular switches involved in the complex oncogenic circuits of gastric cancer.
High MCM7 expression is associated with non-small cell lung cancer.
MCM4 (show MCM4 Antibodies) and MCM7 expression is significantly correlated with Ki-67 (show MKI67 Antibodies), Bmi1 (show BMI1 Antibodies), and cyclin E (show CCNE1 Antibodies) expression in esophageal adenocarcinoma, squamous cell carcinoma and precancerous lesions.
Unique pattern of ORC2 and MCM7 localization during DNA replication licensing in the mouse zygote.
cyclin D1 (show CCND1 Antibodies)/CDK4 (show CDK4 Antibodies) complexes play a direct role in altering an inhibitory RB.MCM7 complex possibly allowing for setting of the origin in preparation for DNA replication
MCM7 may be a highly informative biomarker for cervical cancer.
Substrate preference and helicase (show DNA2 Antibodies) actions of mouse MCM4 (show MCM4 Antibodies)/6/7 helicase (show DNA2 Antibodies) complexes.
Accumulation and dynamics of Mcm7 are described during oogenesis and the first embryonic cell cycle.
cellular DNA replication factor (show CDT1 Antibodies) MCM7 is involved in prostate cancer (CaP) and MCM7 gene expression was reduced by green tea catechins
DNA binding and helicase (show DNA2 Antibodies) activities of Mcm4 (show MCM4 Antibodies)/6/7 are significantly stimulated by Cdt1 (show CDT1 Antibodies)
Mcm2-7 (show MCM2 Antibodies) associate with Cdc45 (show CDC45 Antibodies) and GINS to form a relatively stable CMG (show CASK Antibodies) (Cdc45 (show CDC45 Antibodies)-MCM-GINS) complex.
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
, DNA replication licensing factor MCM7
, homolog of S. cerevisiae Cdc47
, minichromosome maintenance deficient 7
, hypothetical protein
, minichromosome maintenance protein 7
, MCM7 minichromosome maintenance deficient 7
, minichromosome maintenance complex component 7
, DNA replication licensing factor MCM7-like
, minichromosome maintenance complex component 2
, mini chromosome maintenance deficient 7
, CDC47 homolog B
, DNA replication licensing factor mcm7-B
, minichromosome maintenance protein 7-B
, minichromosome maintenance 7
, minichromosome maintenance-PCR1
, CDC47 homolog A
, DNA replication licensing factor mcm7-A
, minichromosome maintenance protein 7-A
, Minichromosome maintenance protein 7