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MDM2 Antibodies

(Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
This gene is a target gene of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues. [provided by RefSeq, Jul 2008].
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 393-424), (C-Term) antibody anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 393-424), (C-Term) antibody anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 393-424), (C-Term) antibody (ABIN388068)

MDM2 Reactivity: Human IHC (p), WB Host: Rabbit Polyclonal RB00757 unconjugated

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (Center) antibody anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (Center) antibody anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (Center) antibody (ABIN2854782)

MDM2 Reactivity: Human, Mouse ChIP, ICC, IF, IP, IHC (p), WB Host: Rabbit Polyclonal unconjugated

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 141-176) antibody anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 141-176) antibody anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 141-176) antibody (ABIN388067)

MDM2 Reactivity: Human FACS, IF, IHC (p), WB Host: Rabbit Polyclonal RB7981 unconjugated

MDM2 Antibodies by Grade

Find MDM2 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

MDM2 Antibodies by Reactivity

Find MDM2 Antibodies for a variety of species such as anti-Human MDM2, anti-Mouse MDM2, anti-Rat MDM2. The species listed below are among those available. Click on a link to go to the corresponding products.

MDM2 Antibodies by Application

Find MDM2 Antibodies validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

MDM2 Antibodies by Host

Find MDM2 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

MDM2 Antibodies by Binding Specificity

Find MDM2 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MDM2 Antibodies by Clonality

Find available monoclonal or polyclonal MDM2 Antibodies. Click on a link to go to the corresponding products.

MDM2 Antibodies by Clone

Find MDM2 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

MDM2 Antibodies by Conjugate

Find MDM2 Antibodies with a specific conjugate such as Biotin, HRP, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MDM2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC (p), PLA, RNAi, ELISA, WB
Validations
  • (6)
Cat. No. ABIN517806
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey, Mouse
Application ELISA, ICC, IF, IHC, WB
Validations
  • (5)
Cat. No. ABIN6256167
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3031734
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (4)
Cat. No. ABIN802548
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application ELISA, ICC, IF, IHC, IP, WB
Validations
  • (4)
Cat. No. ABIN6263177
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC, WB
Validations
  • (4)
Cat. No. ABIN2448039
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IHC, IHC (p), WB
Validations
  • (4)
Cat. No. ABIN1490872
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (3)
Cat. No. ABIN6940031
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application Coat, ELISA, IHC, StM, WB
Validations
  • (3)
Cat. No. ABIN6940030
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IF, IHC, ELISA, WB
Validations
  • (3)
Cat. No. ABIN1533341
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IF, IHC, ELISA, WB
Validations
  • (3)
Cat. No. ABIN1531340
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (3)
Cat. No. ABIN802533
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Rat
Application IC, IF, IP, IHC, WB
Validations
  • (3)
Cat. No. ABIN2957662
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application IC, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN2704976
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN319417
Quantity 0.1 mL
Datasheet Datasheet

Latest Publications for our MDM2 Antibodies

Duan, Ma, Huang, DAmore, Zhang, Lei et al.: "The Clustered, Regularly Interspaced, Short Palindromic Repeats-associated Endonuclease 9 (CRISPR/Cas9)-created MDM2 T309G Mutation Enhances Vitreous-induced Expression of MDM2 and Proliferation and ..." in: The Journal of biological chemistry, Vol. 291, Issue 31, pp. 16339-47, (2017) (PubMed).

Fragou, Tzimagiorgis, Karageorgopoulos, Barbetakis, Lazopoulos, Papaioannou, Haitoglou, Kouidou: "Increased Δ133p53 mRNA in lung carcinoma corresponds with reduction of p21 expression." in: Molecular medicine reports, Vol. 15, Issue 4, pp. 1455-1460, (2017) (PubMed).

Zhou, Duan, Ma, Wu, Hu, Chen, Chee, Cui, Samad, Matsubara, Mukai, DAmore, Lei: "Introduction of the MDM2 T309G Mutation in Primary Human Retinal Epithelial Cells Enhances Experimental Proliferative Vitreoretinopathy." in: Investigative ophthalmology & visual science, Vol. 58, Issue 12, pp. 5361-5367, (2017) (PubMed).

Mokhtarzadeh, Parhiz, Hashemi, Abnous, Ramezani: "P53-Derived peptides conjugation to PEI: an approach to producing versatile and highly efficient targeted gene delivery carriers into cancer cells." in: Expert opinion on drug delivery, Vol. 13, Issue 4, pp. 477-91, (2016) (PubMed).

Guo, Yang, Yang, Linghu, Zhan, Brock, Herman, Zhang, Guo: "RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel." in: Oncotarget, Vol. 6, Issue 6, pp. 4202-13, (2015) (PubMed).

Xiao, Zhou, Yi, Luo, Jiang, Tian, Li, Xue: "Fra-1 is downregulated in cervical cancer tissues and promotes cervical cancer cell apoptosis by p53 signaling pathway in vitro." in: International journal of oncology, Vol. 46, Issue 4, pp. 1677-84, (2015) (PubMed).

Li, Liu, Wang, Fang, Shen, Cai, Gao, Li, Zhang, Ye: "The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer." in: The Journal of biological chemistry, Vol. 290, Issue 37, pp. 22649-61, (2015) (PubMed).

Liao, Xiao, Zhu, Zheng, He, Pei, Li, Zhou: "CD38 is highly expressed and affects the PI3K/Akt signaling pathway in cervical cancer." in: Oncology reports, Vol. 32, Issue 6, pp. 2703-9, (2014) (PubMed).

Khoronenkova, Dianova, Parsons, Dianov: "USP7/HAUSP stimulates repair of oxidative DNA lesions." in: Nucleic acids research, Vol. 39, Issue 7, pp. 2604-9, (2011) (PubMed).

Lei, Velez, Kazlauskas: "Pathological signaling via platelet-derived growth factor receptor {alpha} involves chronic activation of Akt and suppression of p53." in: Molecular and cellular biology, Vol. 31, Issue 9, pp. 1788-99, (2011) (PubMed).

Aliases for MDM2 Antibodies

MDM2 proto-oncogene (MDM2) Antibodies
MDM2 proto-oncogene S homeolog (mdm2.S) Antibodies
MDM2 proto-oncogene (Mdm2) Antibodies
Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) (MDM2) Antibodies
MDM2 oncogene, E3 ubiquitin protein ligase (mdm2) Antibodies
transformed mouse 3T3 cell double minute 2 (Mdm2) Antibodies
1700007J15Rik Antibodies
AA415488 Antibodies
ACTFS Antibodies
hdm2 Antibodies
HDMX Antibodies
Mdm-2 Antibodies
zgc:109834 Antibodies
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