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DOCK8 Products

(Dedicator of Cytokinesis 8 (DOCK8))

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This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010].

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Featured DOCK8 Categories

DOCK8 Antibodies

High quality antibodies with extensive validation data.

Recommended DOCK8 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7149603
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN1491684
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6242950
Quantity 200 μL
Datasheet Datasheet

Recommended DOCK8 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6211962
Quantity 96 tests
Datasheet Datasheet

Recommended DOCK8 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2719642
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our DOCK8 products

Johansson, Tabor, Wikell, Jalkanen, Fuxe: "TGF-β1-Induced Epithelial-Mesenchymal Transition Promotes Monocyte/Macrophage Properties in Breast Cancer Cells." in: Frontiers in oncology, Vol. 5, pp. 3, (2015) (PubMed).

Jabara, McDonald, Janssen, Massaad, Ramesh, Borzutzky, Rauter, Benson, Schneider, Baxi, Recher, Notarangelo, Wakim, Dbaibo, Dasouki, Al-Herz, Barlan, Baris, Kutukculer, Ochs, Plebani, Kanariou et al.: "DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. ..." in: Nature immunology, Vol. 13, Issue 6, pp. 612-20, (2012) (PubMed).

Synonyms and alternative names related to DOCK8

dedicator of cytokinesis 8 (dock8), dedicator of cytokinesis 8 (DOCK8), dedicator of cytokinesis 8 (Dock8), 1200017A24Rik, 5830472H07Rik, A130095G14Rik, AI461977, im:7154406, MRD2, si:dkey-91m11.1, ZIR8

Protein level used designations for DOCK8

  • dedicator of cytokinesis 8
  • dedicator of cytokinesis protein 8-like
  • 1200017A24Rik
  • dedicator of cytokinesis protein 8
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