DOCK8 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2719642

Product Details

Target: DOCK8 (Dedicator of Cytokinesis 8 (DOCK8))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This DOCK8 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human DOCK8 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: DOCK8 (Dedicator of Cytokinesis 8 (DOCK8))

Alternative Name: Dock8 (DOCK8 Products)

Synonyms: im:7154406 Protein, si:dkey-91m11.1 Protein, MRD2 Protein, ZIR8 Protein, 1200017A24Rik Protein, 5830472H07Rik Protein, A130095G14Rik Protein, AI461977 Protein, dedicator of cytokinesis 8 Protein, dock8 Protein, DOCK8 Protein, Dock8 Protein

Background: This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010].

Molecular Weight: 238.3 kDa

NCBI Accession: NP_982272