EBP Products
(Emopamil Binding Protein (Sterol Isomerase) (EBP))
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The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2\; also known as Conradi-Hunermann syndrome). [provided by RefSeq, Jul 2008].
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Featured EBP Categories
EBP Antibodies
High quality antibodies with extensive validation data.
EBP ELISA Kits
Reliable ELISA kits for a wide range of species.
EBP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended EBP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7142288
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
- (2)
Cat. No.
ABIN1881278
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN652952
Quantity
400 μL
Datasheet
Datasheet
Recommended EBP ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1118975
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1118974
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1118973
Quantity
96 tests
Datasheet
Datasheet
Recommended EBP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (4)
Cat. No.
ABIN3100004
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3120933
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2712409
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our EBP products
: "Two novel EBP mutations in Conradi-Hünermann-Happle syndrome." in: European journal of dermatology : EJD, Vol. 18, Issue 4, pp. 391-3, (2008) (PubMed).: "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations." in: Journal of lipid research, Vol. 49, Issue 12, pp. 2582-9, (2008) (PubMed).
: "Novel EBP gene mutations in Conradi-Hünermann-Happle syndrome." in: The British journal of dermatology, Vol. 157, Issue 6, pp. 1225-9, (2007) (PubMed).
Synonyms and alternative names related to EBP
emopamil binding protein (sterol isomerase) (Ebp), emopamil binding protein (sterol isomerase) L homeolog (ebp.L), emopamil binding protein (sterol isomerase) (ebp), emopamil binding protein (sterol isomerase) (EBP), phenylalkylamine Ca2+ antagonist (emopamil) binding protein (Ebp), AI255399, cdpx2, CDPX2, cho2, CHO2, cpx, CPX, cpxd, CPXD, mSI, Pabp, Td, zgc:91895Protein level used designations for EBP
- 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
- D8-D7 sterol isomerase
- emopamil-binding protein
- cholestenol Delta-isomerase
- phenylalkylamine binding protein
- delta(8)-Delta(7) sterol isomerase
- emopamil binding protein (sterol isomerase)
- 3-beta-hydroxysteroid-delta-8,delta-7-isomerase
- Chondrodysplasia punctata-2, X-linked dominant (Happle syndrome)
- emopamil-binding protein (sterol isomerase)
- sterol 8-isomerase
- phenylalkylamine Ca2+ antagonist (emopamil) binding protein
- tattered
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