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Human Monoclonal TDGF1 Primary Antibody for FACS - ABIN4897519
Watanabe, Bianco, Strizzi, Hamada, Mancino, Bailly, Mo, Wen, Miatkowski, Gonzales, Sanicola, Seno, Salomon: Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration. in The Journal of biological chemistry 2007
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Human Polyclonal TDGF1 Primary Antibody for ICC, FACS - ABIN151145
Sun, Shi, Li, Jiang, Fu, Guo: Lefty inhibits glioma growth by suppressing Nodal-activated Smad and ERK1/2 pathways. in Journal of the neurological sciences 2014
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Human Polyclonal TDGF1 Primary Antibody for ELISA, IHC - ABIN4300489
Lee, Jung, Cho, Kim, Lee, Kim, Lee, Shim: GRP78 Protein Expression as Prognostic Values in Neoadjuvant Chemoradiotherapy and Laparoscopic Surgery for Locally Advanced Rectal Cancer. in Cancer research and treatment : official journal of Korean Cancer Association 2015
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Human Monoclonal TDGF1 Primary Antibody for ELISA, WB - ABIN967164
van Dijk, van Den Akker, Amelsvoort, Mano, Löwenberg, von Lindern: Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells. in Blood 2000
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Results identified elevated CR-1 (show CR1 Antibodies) expression in esophageal squamous cell carcinoma (ESCC) specimens which correlated to poor prognosis of the patients. CR-1 (show CR1 Antibodies) high cells isolated from ESCC cells possess cancer stem-like cells (ECSLC) properties.
These results highlight a functional role for CRIPTO and GRP78 (show HSPA5 Antibodies) in prostate cancer metastasis and suggest that targeting CRIPTO/GRP78 (show HSPA5 Antibodies) signaling may have significant therapeutic potential.
PGAP6 plays a critical role in Nodal signaling modulation through CRIPTO shedding.
Upregulation of cripto-1 (show CFC1 Antibodies) is associated with prostate cancer.
the miR (show MLXIP Antibodies)-15b expression is negatively associated with the cripto-1 (show CFC1 Antibodies) expression in glioma cells. miR (show MLXIP Antibodies)-15b may subsequently impair growth and invasion of glioma cells through targeted regulation of cripto-1 (show CFC1 Antibodies).
These findings suggest that CRIPTO expression may be a useful serological marker for diagnostic and/or prognostic purposes during germ cell cancer management.
serum CR-1 (show CR1 Antibodies) is a useful diagnostic and prognostic marker for nonsmall cell lung cancer patients.
Cripto-1 (show CFC1 Antibodies) overexpression contributes to aggressiveness and poor prognosis of hepatocellular carcinoma
The main signaling pathways mediating Cripto-1 (show CFC1 Antibodies) effects include Nodal-dependent (Smad2 (show SMAD2 Antibodies)/3) and Nodal-independent (Src (show SRC Antibodies)/p44 (show GTF2H2 Antibodies)/42/Akt (show AKT1 Antibodies)) signaling transduction pathways
Cripto-1 (show CFC1 Antibodies) is a novel and dynamically regulated effector of stem cell functions in colorectal cancer.
MEF2C (show MEF2C Antibodies) has a role in regulating outflow tract alignment and transcriptional control of Tdgf1
Dissection of the mechanism by which this occurs indicates that mCripto-1 activates receptor activator NF-kappaB (show NFKB1 Antibodies)/receptor activator NF-kappaB (show NFKB1 Antibodies) ligand, and NF-kappaB (show NFKB1 Antibodies) signaling pathways.
our findings strongly suggest that Cripto-1 (show CFC1 Antibodies) is a potential driver of mammary tumorigenesis
CR1 protein fragments bind tightly to PfRh4 and also function as soluble inhibitors to block PfRh4 binding to red blood cells and to inhibit the PfRh4-CR1 invasion pathway
Data show that Cripto haploinsufficiency may be associated with increased tumorigenesis, suggesting that the effect of Cripto on tumor development is more complex and may strongly depend on the cellular context.
Cripto is transiently expressed in early differentiating myocardial cells of the left ventricle, right ventricle and outflow tract between late head fold stages and E8.5.
Cripto plays a critical role during mouse gastrulation, especially in mesoderm and endoderm formation
Cripto, a regulator of early embryogenesis, is a novel regulator of muscle regeneration and satellite cell progression toward the myogenic lineage.
These data suggest that Cripto/GRP78 signaling is an important pathway that regulates hematopoietic stem cell quiescence.
Late zygotic oep mutants have strongly reduced or absent pitx2 (show PITX2 Antibodies) expression in the lateral plate mesoderm (LPM), but this expression can be rescued to strong levels by restoring oep in midline structures only.
Nodal-BMP signaling cascade drives left-right heart morphogenesis by regulating the speed and direction of cardiomyocyte movement
Using mutants in the Nodal receptor cofactor one-eyed pinhead (oep) and the T-box transcription factors spadetail (spt (show AGXT Antibodies)) and no tail (ntl), we were able to define distinctive regulation underlying these sequential phases of PGP midline migration
heterozygote mutations in fgf8 (show FGF8 Antibodies), shh (show SHH Antibodies) or oep lead to a reduced number of ascending dopaminergic neurons in zebrafish and may confer increased susceptibility to the Parkinson disease
Vg1 and GDF1 (show GDF1 Antibodies) signaling require one-eyed pinhead.
Interplay between FGF, one-eyed pinhead (zoep), and T-box transcription factors spt (show AGXT Antibodies) and ntl during zebrafish posterior
Spatial and temporal regulation of FRL1 protein expression during the gastrula stage are demonstrated.
findings show that vegetal cell-specific translational repression of xCR1 mRNA contributes to the spatially restricted accumulation of the xCR1 protein in Xenopus embryos
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.
cripto-1 growth factor
, epidermal growth factor-like cripto protein CR1
, TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR)
, cripto growth factor
, epidermal growth factor-like Cripto protein
, teratocarcinoma-derived growth factor
, cryptic protein
, one eyed pinhead
, teratocarcinoma-derived growth factor 1
, fibroblast growth factor receptor ligand 1
, teratocarcinoma-derived growth factor 3