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EIF3C Products

(Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

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Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (By similarity).

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Featured EIF3C Categories

EIF3C Antibodies

High quality antibodies with extensive validation data.

EIF3C Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EIF3C Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC
Validations
  • (4)
Cat. No. ABIN7262965
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN7152149
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application EIA, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN952048
Quantity 0.4 mL
Datasheet Datasheet

Recommended EIF3C ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6204049
Quantity 96 tests
Datasheet Datasheet

Recommended EIF3C Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092273
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136639
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2720074
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our EIF3C products

Jin, Oda, Chen, Yang, Zhou, Kang, Valentine, Kefauver, Liao, Zhang, Gonzalez-Martin, Shepherd, Morgan, Mondala, Head, Kim, Xiao, Fu, Liu, Han, Williamson, Xiao: "Differential Sensitivity of Target Genes to Translational Repression by miR-17~92." in: PLoS genetics, Vol. 13, Issue 2, pp. e1006623, (2017) (PubMed).

Chazal, Daguenet, Wendling, Ulryck, Tomasetto, Sargueil, Le Hir: "EJC core component MLN51 interacts with eIF3 and activates translation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 15, pp. 5903-8, (2013) (PubMed).

Synonyms and alternative names related to EIF3C

eukaryotic translation initiation factor 3, subunit C (eif3c), eukaryotic translation initiation factor 3 subunit C (LOC454016), eukaryotic translation initiation factor 3 subunit C (LOC479795), eukaryotic translation initiation factor 3, subunit C (EIF3C), eukaryotic translation initiation factor 3 subunit 8 (Smp_000480), eukaryotic translation initiation factor 3 subunit C (eif3c), Eukaryotic translation initiation factor 3 subunit C (eIF3c), eukaryotic translation initiation factor 3 subunit C (ANI_1_1094124), eukaryotic translation initiation factor 3 subunit C (AOR_1_578054), eukaryotic translation initiation factor 3 subunit C (PTRG_08272), translation initiation factor eIF3c (SJAG_04981), eukaryotic translation initiation factor 3 subunit C (TERG_03202), translation initiation factor eIF-3 subunit 8 (PGTG_09255), eukaryotic translation initiation factor 3 subunit C (Tsp_05110), eukaryotic translation initiation factor 3 subunit C (Eif3c), eukaryotic translation initiation factor 3 subunit C (EIF3C), eukaryotic translation initiation factor 3, subunit C (Eif3c), eukaryotic translation initiation factor 3 subunit C L homeolog (eif3c.L), eukaryotic translation initiation factor 3, subunit C-like (EIF3CL), Eukaryotic translation initiation factor 3 subunit C (eif-3.C), 110kDa, 3230401O13Rik, AO090011000340, eif3-p110, eIF3-p110, eIF3-S8, eIF3c, EIF3C, EIF3CL, eif3s8, EIF3S8, Eif3s8, fi37c04, LOC733086, NIPIL(A3), NipilA3, wu:fb34a08, wu:fi37c04, Xs, Xsl, zgc:66128

Protein level used designations for EIF3C

  • eukaryotic translation initiation factor 3 subunit 8
  • eukaryotic translation initiation factor 3 subunit C
  • eukaryotic translation initiation factor 3, subunit 8, 110kDa
  • eIF3 p110
  • Eukaryotic translation initiation factor 3 subunit 8
  • eIF3-S8 protein
  • Eukaryotic translation initiation factor 3 subunit C
  • cell migration-inducing protein 17
  • eukaryotic translation initiation factor 3, subunit 8 (110kD)
  • NIPI-like protein
  • eukaryotic translation initiation factor 3, subunit 8 (110 kDa)
  • extra-toes spotting
  • eukaryotic translation initiation factor 3, subunit C
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