FCGR3A Proteins
(Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
| Catalog no. | Product | Reactivity | Host / Clonality | Application | Price & lead time |
|---|---|---|---|---|---|
| FCGR3A Protein (AA 24-190) (His tag) | Mouse | Bacteria |
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$500.50
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| FCGR3A Protein (AA 1-208) (His tag) | Human | Eukaryota |
|
$500.50
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| FCGR3A Protein (AA 26-108) (His tag) | Human | Bacteria |
|
$426.25
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|
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| FCGR3A Protein (AA 17-208) (His tag) | Human | Bacteria |
|
$500.50
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|
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| FCGR3A Protein (Fc Tag) | Cynomolgus | HEK-293 Cells |
|
$530.77
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|
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| FCGR3A Protein (His tag) | Human | Escherichia coli (E. coli) |
|
$478.00
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| FCGR3A Protein (His tag) | Human | Escherichia coli (E. coli) |
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$478.00
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|
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| FCGR3A Protein (AA 17-208, V176F) (His tag) | Human | Human Cells |
|
$792.31
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| FCGR3A Protein (His tag) | Human | Mammalian Cells |
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$705.00
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|
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| FCGR3A Protein (His tag) | Human | Human Cells |
|
$510.40
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|
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| FCGR3A Protein (His tag) | Human | Human Cells |
|
$554.40
View price
|
Catalog No. ABIN7819796
$500.50
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to:
United States
Delivery in 7 to 10 Business Days
Catalog No. ABIN7813472
$500.50
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to:
United States
Delivery in 7 to 10 Business Days
Catalog No. ABIN7815266
$426.25
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to:
United States
Delivery in 7 to 10 Business Days
Catalog No. ABIN7815267
$500.50
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to:
United States
Delivery in 7 to 10 Business Days
Protein
- Origin
- Cynomolgus
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7794637
$530.77
Plus shipping costs $50.00
50 μg
Shipping to:
United States
Delivery in 2 to 4 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Imm (Immunogen: Listed application)
- ELISA (ELISA: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
Catalog No. ABIN7941317
$478.00
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 8 to 12 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Imm (Immunogen: Listed application)
- ELISA (ELISA: Listed application)
- Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
Catalog No. ABIN7950993
$478.00
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 8 to 12 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- ELISA (ELISA: Listed application)
- MS (Mass Spectrometry: Listed application)
- Origin
- Human
- Host
- Human Cells
- Protein Type
- Recombinant
- Purity
- Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7314144
$792.31
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 8 to 11 Business Days
Protein
- SDS (SDS-PAGE: Listed application)
- WB (Western Blotting: Listed application)
- Imm (Immunogen: Listed application)
- ELISA (ELISA: Listed application)
- Origin
- Human
- Host
- Mammalian Cells
- Protein Type
- Recombinant
Catalog No. ABIN7946819
$705.00
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 8 to 12 Business Days
Protein
- Origin
- Human
- Host
- Human Cells
- Protein Type
- Recombinant
- Purity
- Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7959459
$510.40
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 8 to 12 Business Days
Protein
- Origin
- Human
- Host
- Human Cells
- Protein Type
- Recombinant
- Purity
- Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7961605
$554.40
Plus shipping costs $50.00
50 μg
(More quantities available)
Shipping to:
United States
Delivery in 8 to 12 Business Days
Latest Publications for our FCGR3A Proteins
: "FcγR Binding and ADCC Activity of Human IgG Allotypes." in: Frontiers in immunology, Vol. 11, pp. 740, (2020) (PubMed).
: "Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies." in: mAbs, Vol. 11, Issue 5, pp. 826-836, (2020) (PubMed).
: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).
: "Identification of anti-CD16a single domain antibodies and their application in bispecific antibodies." in: Cancer biology & therapy, pp. 1-9, (2019) (PubMed).
: "Structural and functional characterization of MBS301, an afucosylated bispecific anti-HER2 antibody." in: mAbs, Vol. 10, Issue 6, pp. 864-875, (2019) (PubMed).
: "Charge variant analysis of proposed biosimilar to Trastuzumab." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 46, pp. 46-56, (2017) (PubMed).
: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).
: "Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9986-93, (2009) (PubMed).
: "Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies." in: mAbs, Vol. 11, Issue 5, pp. 826-836, (2020) (PubMed).
: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).
: "Identification of anti-CD16a single domain antibodies and their application in bispecific antibodies." in: Cancer biology & therapy, pp. 1-9, (2019) (PubMed).
: "Structural and functional characterization of MBS301, an afucosylated bispecific anti-HER2 antibody." in: mAbs, Vol. 10, Issue 6, pp. 864-875, (2019) (PubMed).
: "Charge variant analysis of proposed biosimilar to Trastuzumab." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 46, pp. 46-56, (2017) (PubMed).
: "Fc gamma receptor glycosylation modulates the binding of IgG glycoforms: a requirement for stable antibody interactions." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5471-85, (2014) (PubMed).
: "Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9986-93, (2009) (PubMed).
Aliases for FCGR3A Proteins
Fc fragment of IgG receptor IIIa (FCGR3A) ProteinsFc fragment of IgG receptor IIIa (Fcgr3a) Proteins
CD16 Proteins
CD16A Proteins
FCG3 Proteins
FCGR3 Proteins
Fcgr4 Proteins
FCGRIII Proteins
FCR-10 Proteins
FCRIII Proteins
FCRIIIA Proteins
IGFR3 Proteins
Did you look for something else?
- FCGR2B Proteins
- FCGR2A Proteins
- FCGR1A Proteins
- FCGR1 Proteins
- FCGBP Proteins
- FCF1 Proteins
- FCER2 Proteins
- FCAR Proteins
- FCAMR Proteins
- Fc Receptor, IgG, Low Affinity IV Proteins
- Fc gamma RII Proteins
- Fc epsilon RI/FCER1A Proteins
- FBXW9 Proteins
- FBXW8 Proteins
- FBXW7 Proteins
- FBXW5 Proteins
- FBXW4 Proteins
- FBXW2 Proteins
- FBXW11 Proteins
- FBXO9 Proteins
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