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FGD4 Products

(FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq, Oct 2008].

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Featured FGD4 Categories

FGD4 Antibodies

High quality antibodies with extensive validation data.

FGD4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FGD4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (4)
Cat. No. ABIN2856709
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN656907
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6140588
Quantity 100 μL
Datasheet Datasheet

Recommended FGD4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3080181
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136852
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2721030
Quantity 20 μg
Datasheet Datasheet

Synonyms and alternative names related to FGD4

FYVE, RhoGEF and PH domain containing 4 (FGD4), FYVE, RhoGEF and PH domain containing 4 (Fgd4), 9030023J02Rik, 9330209B17Rik, CMT4H, FRABP, Frabp, ZFYVE6

Protein level used designations for FGD4

  • FGD1 family, member 4
  • FGD1-related F-actin-binding protein
  • FYVE, RhoGEF and PH domain-containing protein 4
  • actin-filament binding protein frabin
  • zinc finger FYVE domain-containing protein 6
  • Fgd1-related F-actin-binding protein
  • actin filament-binding protein frabin
  • frabin
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