FLT1 Products
(Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
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This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009].
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Featured FLT1 Categories
FLT1 Antibodies
High quality antibodies with extensive validation data.
FLT1 ELISA Kits
Reliable ELISA kits for a wide range of species.
FLT1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FLT1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
- (4)
- (6)
Cat. No.
ABIN725795
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (1)
- (5)
Cat. No.
ABIN6140687
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
Cat. No.
ABIN6256626
Quantity
100 μL
Datasheet
Datasheet
Recommended FLT1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1059785
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Goat
Analytical Method
Competition ELISA
Validations
Cat. No.
ABIN1059788
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1059790
Quantity
96 tests
Datasheet
Datasheet
Recommended FLT1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7275835
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275836
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
Cat. No.
ABIN5570127
Quantity
5 μg
Datasheet
Datasheet
Latest Publications for our FLT1 products
: "Tumor Microenvironment Modulates Immunological Outcomes of Myeloid Cells with mTORC1 Disruption." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 202, Issue 5, pp. 1623-1634, (2019) (PubMed).: "MMP14-Containing Exosomes Cleave VEGFR1 and Promote VEGFA-Induced Migration and Proliferation of Vascular Endothelial Cells." in: Investigative ophthalmology & visual science, Vol. 60, Issue 6, pp. 2321-2329, (2019) (PubMed).
: "Modulating circulating sFlt1 in an animal model of preeclampsia using PAMAM nanoparticles for siRNA delivery." in: Placenta, Vol. 58, pp. 1-8, (2018) (PubMed).
: "Ferrochelatase is a therapeutic target for ocular neovascularization." in: EMBO molecular medicine, Vol. 9, Issue 6, pp. 786-801, (2018) (PubMed).
: "Experimental Models of Endotheliopathy: Impact of Shock Severity." in: Shock (Augusta, Ga.), Vol. 49, Issue 5, pp. 564-571, (2018) (PubMed).
: "Sesquiterpene binding Gly-Leu-Ser/Lys-"co-adaptation pocket" to inhibit lung cancer cell epithelial-mesenchymal transition." in: Oncotarget, Vol. 8, Issue 41, pp. 70192-70203, (2018) (PubMed).
: "Hsp90β promotes aggressive vasculogenic mimicry via epithelial-mesenchymal transition in hepatocellular carcinoma." in: Oncogene, (2018) (PubMed).
: "Ferulic acid alleviates symptoms of preeclampsia in rats by upregulating vascular endothelial growth factor." in: Clinical and experimental pharmacology & physiology, Vol. 44, Issue 10, pp. 1026-1031, (2018) (PubMed).
: "A quantitative method for screening and identifying molecular targets for nanomedicine." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 263, pp. 57-67, (2018) (PubMed).
: "Placental soluble fms-like tyrosine kinase expression in small for gestational age infants and risk for adverse outcomes." in: Placenta, Vol. 52, pp. 10-16, (2018) (PubMed).
Synonyms and alternative names related to FLT1
fms related tyrosine kinase 1 (FLT1), FMS-related tyrosine kinase 1 (Flt1), vascular endothelial growth factor receptor 1 (CpipJ_CPIJ012087), fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (flt1), FMS-like tyrosine kinase 1 (Flt1), fms related tyrosine kinase 1 (Flt1), vascular endothelial growth factor receptor-1 (FLT-1), AI323757, FLT, FLT-1, Flt-1, FLT1, flt1b, sFlt1, VEGFR-1, VEGFR1Protein level used designations for FLT1
- fms-like tyrosine kinase 1
- fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- tyrosine-protein kinase FRT
- tyrosine-protein kinase receptor FLT
- vascular endothelial growth factor receptor 1
- vascular permeability factor receptor
- FLT-1
- FMS-like tyrosine kinase 1
- Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
- vascular endothelial growth factor receptor-1
- fms-related tyrosine kinase 1
- receptor tyrosine kinase Flt1b
- soluble fms-like tyrosine kinase 1
- embryonic receptor kinase 2
- VEGFR-1
- vascular endothelial growth factor/vascular permeability factor receptor
- ascular endothelial growth factor/vascular permeability factor receptor
- VEGF-receptor
- flt-receptor
- vascular endothelial growth factor 1
- flt-1 type VEGF receptor
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