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FLT1 Products

(Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Categories

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009].

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Featured FLT1 Categories

FLT1 Antibodies

High quality antibodies with extensive validation data.

FLT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

FLT1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FLT1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (4)
  • (6)
Cat. No. ABIN725795
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (4)
Cat. No. ABIN6256626
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IHC (p), WB
Validations
  • (1)
  • (3)
Cat. No. ABIN653260
Quantity 400 μL
Datasheet Datasheet

Recommended FLT1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955934
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6963502
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (1)
Cat. No. ABIN6955933
Quantity 96 tests
Datasheet Datasheet

Recommended FLT1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (2)
Cat. No. ABIN2181915
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN6253654
Quantity 100 μg
Datasheet Datasheet
Reactivity Rhesus Monkey
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN5955010
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FLT1 products

Ding, Sun, Wu, Hu, Zhang, Yan: "Tumor Microenvironment Modulates Immunological Outcomes of Myeloid Cells with mTORC1 Disruption." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 202, Issue 5, pp. 1623-1634, (2019) (PubMed).

Han, Chang, Azar: "MMP14-Containing Exosomes Cleave VEGFR1 and Promote VEGFA-Induced Migration and Proliferation of Vascular Endothelial Cells." in: Investigative ophthalmology & visual science, Vol. 60, Issue 6, pp. 2321-2329, (2019) (PubMed).

Yu, Jia, Guo, Chen, Feng: "Modulating circulating sFlt1 in an animal model of preeclampsia using PAMAM nanoparticles for siRNA delivery." in: Placenta, Vol. 58, pp. 1-8, (2018) (PubMed).

Basavarajappa, Sulaiman, Qi, Shetty, Sheik Pran Babu, Sishtla, Lee, Quigley, Alkhairy, Briggs, Gupta, Tang, Shadmand, Grant, Boulton, Seo, Corson: "Ferrochelatase is a therapeutic target for ocular neovascularization." in: EMBO molecular medicine, Vol. 9, Issue 6, pp. 786-801, (2018) (PubMed).

Hofmann, Zipperle, Jafarmadar, Ashmwe, Keibl, Penzenstadler, Ponschab, Jafarmadar, Redl, Bahrami, Schöchl: "Experimental Models of Endotheliopathy: Impact of Shock Severity." in: Shock (Augusta, Ga.), Vol. 49, Issue 5, pp. 564-571, (2018) (PubMed).

Ai, Zhang, Gao, Qin, Zhong, Gu, Li, Qiao, Tian, Cui, Yang, Bi, Xiao, Chen, Liu, Zhou, Sun, Yang: "Sesquiterpene binding Gly-Leu-Ser/Lys-"co-adaptation pocket" to inhibit lung cancer cell epithelial-mesenchymal transition." in: Oncotarget, Vol. 8, Issue 41, pp. 70192-70203, (2018) (PubMed).

Meng, Chen, Lei, Han, Zhong, Wang, Liu, Gao, Zhang, Tan, Liu, Zhou, Sun, Yang: "Hsp90β promotes aggressive vasculogenic mimicry via epithelial-mesenchymal transition in hepatocellular carcinoma." in: Oncogene, (2018) (PubMed).

Gong, Wan, Yuan, Man, Zhang: "Ferulic acid alleviates symptoms of preeclampsia in rats by upregulating vascular endothelial growth factor." in: Clinical and experimental pharmacology & physiology, Vol. 44, Issue 10, pp. 1026-1031, (2018) (PubMed).

Guo, Yang, Bielenberg, Dillon, Zurakowski, Moses, Auguste: "A quantitative method for screening and identifying molecular targets for nanomedicine." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 263, pp. 57-67, (2018) (PubMed).

Spiel, Salahuddin, Pernicone, Zsengeller, Wang, Modest, Karumanchi, Hecht: "Placental soluble fms-like tyrosine kinase expression in small for gestational age infants and risk for adverse outcomes." in: Placenta, Vol. 52, pp. 10-16, (2018) (PubMed).

Synonyms and alternative names related to FLT1

fms related tyrosine kinase 1 (FLT1), FMS-related tyrosine kinase 1 (Flt1), vascular endothelial growth factor receptor 1 (CpipJ_CPIJ012087), fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (flt1), FMS-like tyrosine kinase 1 (Flt1), fms related tyrosine kinase 1 (Flt1), vascular endothelial growth factor receptor-1 (FLT-1), AI323757, FLT, FLT-1, Flt-1, FLT1, flt1b, sFlt1, VEGFR-1, VEGFR1

Protein level used designations for FLT1

  • fms-like tyrosine kinase 1
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • tyrosine-protein kinase FRT
  • tyrosine-protein kinase receptor FLT
  • vascular endothelial growth factor receptor 1
  • vascular permeability factor receptor
  • FLT-1
  • FMS-like tyrosine kinase 1
  • Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • vascular endothelial growth factor receptor-1
  • fms-related tyrosine kinase 1
  • receptor tyrosine kinase Flt1b
  • soluble fms-like tyrosine kinase 1
  • embryonic receptor kinase 2
  • VEGFR-1
  • vascular endothelial growth factor/vascular permeability factor receptor
  • ascular endothelial growth factor/vascular permeability factor receptor
  • VEGF-receptor
  • flt-receptor
  • vascular endothelial growth factor 1
  • flt-1 type VEGF receptor
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