FYB Products
(FYN-Binding Protein (FYB))
Categories
The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].
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Featured FYB Categories
FYB Antibodies
High quality antibodies with extensive validation data.
FYB ELISA Kits
Reliable ELISA kits for a wide range of species.
FYB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FYB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, ICC, IF, IHC
Validations
- (3)
Cat. No.
ABIN6261835
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN3184706
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN7267283
Quantity
100 μL
Datasheet
Datasheet
Recommended FYB ELISA Kits
Recommended FYB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
Cat. No.
ABIN3131606
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN3092729
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2721484
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our FYB products
: "The adapter proteins ADAP and Nck cooperate in T cell adhesion." in: Molecular immunology, Vol. 60, Issue 1, pp. 72-9, (2014) (PubMed).: "Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1." in: Science (New York, N.Y.), Vol. 316, Issue 5825, pp. 754-8, (2007) (PubMed).
: "Adhesion and degranulation-promoting adapter protein (ADAP) positively regulates T cell sensitivity to antigen and T cell survival." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 3559-69, (2007) (PubMed).
: "The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes." in: Nature reviews. Immunology, Vol. 6, Issue 11, pp. 799-812, (2006) (PubMed).
: "Adaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: differential involvement of the FYB SH3 domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 20, pp. 11527-32, (2001) (PubMed).
: "Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap." in: Science (New York, N.Y.), Vol. 293, Issue 5538, pp. 2260-3, (2001) (PubMed).
Synonyms and alternative names related to FYB
FYN-binding protein (fyb), FYN binding protein 1 (FYB1), FYN binding protein (Fyb), FYN binding protein 1 (Fyb1), ADAP, B630013F22Rik, fyb, FYB-120/130, p120/130, p120/p130, PRO0823, RGD1563421, SLAP-130, Slap130Protein level used designations for FYB
- FYN-binding protein
- FYB-120/130
- FYN-T-binding protein
- SLP-76-associated phosphoprotein
- adhesion and degranulation-promoting adaptor protein
- p120/p130
- FYN binding protein FYB-130
- adhesion and degranulation promoting adaptor protein
- FYN binding protein (FYB-120/130)
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