The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008].
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Latest Publications for our Galanin Receptor 1 products
Barson, Chang, Poon, Morganstern, Leibowitz: "Galanin and the orexin 2 receptor as possible regulators of enkephalin in the paraventricular nucleus of the hypothalamus: relation to dietary fat." in: Neuroscience, Vol. 193, pp. 10-20, (2011) (PubMed).
Henson, Neubig, Jang, Ogawa, Zhang, Carey, DSilva: "Galanin receptor 1 has anti-proliferative effects in oral squamous cell carcinoma." in: The Journal of biological chemistry, Vol. 280, Issue 24, pp. 22564-71, (2005) (PubMed).
Synonyms and alternative names related to Galanin Receptor 1