GP5 Products
(Glycoprotein V (Platelet) (GP5))
Categories
Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998
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Featured GP5 Categories
GP5 Antibodies
High quality antibodies with extensive validation data.
GP5 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended GP5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7433405
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7440017
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (2)
Cat. No.
ABIN7074111
Quantity
100 μL
Datasheet
Datasheet
Recommended GP5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967156
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883131
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6386284
Quantity
96 tests
Datasheet
Datasheet
Recommended GP5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3080931
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3131301
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3113548
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GP5 products
: "Characterization of monoclonal antibodies against mouse and rat platelet glycoprotein V (CD42d)." in: Hybridoma, Vol. 19, Issue 6, pp. 455-61, (2001) (PubMed).: "Functional conservation of platelet glycoprotein V promoter between mouse and human megakaryocytes." in: Experimental hematology, Vol. 28, Issue 7, pp. 802-14, (2000) (PubMed).
: "Gene cloning of rat and mouse platelet glycoprotein V: identification of megakaryocyte-specific promoters and demonstration of functional thrombin cleavage." in: Blood, Vol. 89, Issue 9, pp. 3253-62, (1997) (PubMed).
: "Novel monoclonal antibody reactive with thrombin-sensitive 74-kDa glycoproteins present on platelets and megakaryocytes both from mouse and rat." in: Hybridoma, Vol. 14, Issue 4, pp. 361-7, (1996) (PubMed).
: "Glycoproteins V and Ib-IX form a noncovalent complex in the platelet membrane." in: The Journal of biological chemistry, Vol. 267, Issue 1, pp. 364-9, (1992) (PubMed).
Synonyms and alternative names related to GP5
glycoprotein V platelet L homeolog (gp5.L), glycoprotein V platelet (GP5), glycoprotein 5 (platelet) (Gp5), glycoprotein V (platelet) (Gp5), glycoprotein V platelet (Gp5), glycoprotein V (platelet) (GP5), CD42d, GPV, lib, PLGPVProtein level used designations for GP5
- glycoprotein 5 (platelet)
- platelet glycoprotein V
- glycoprotein V (platelet)
- platelet glycoprotein V-like
- GPV
- Platelet glycoprotein 5
- Platelete glycoprotein 5
- glycoprotein 5, platelet
- glycoprotein 5
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