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GPAM Products

(Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM))

Categories

This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011].

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Featured GPAM Categories

GPAM Antibodies

High quality antibodies with extensive validation data.

GPAM ELISA Kits

Reliable ELISA kits for a wide range of species.

GPAM Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended GPAM Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7154155
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN709121
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN654109
Quantity 400 μL
Datasheet Datasheet

Recommended GPAM ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956238
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956239
Quantity 96 tests
Datasheet Datasheet

Recommended GPAM Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN7477830
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1355513
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3080915
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GPAM products

Nakajima, Tanaka, Kanbe, Hara, Kamijo, Zhang, Gonzalez, Aoyama et al.: "Bezafibrate at clinically relevant doses decreases serum/liver triglycerides via down-regulation of sterol regulatory element-binding protein-1c in mice: a novel peroxisome proliferator-activated ..." in: Molecular pharmacology, Vol. 75, Issue 4, pp. 782-92, (2009) (PubMed).

Zhao, Chen, Li, Konrad, Cao: "The microsomal cardiolipin remodeling enzyme acyl-CoA lysocardiolipin acyltransferase is an acyltransferase of multiple anionic lysophospholipids." in: Journal of lipid research, Vol. 50, Issue 5, pp. 945-56, (2009) (PubMed).

Li, Sugiyama, Yokoyama, Jiang, Tanaka, Aoyama: "Molecular mechanism of age-specific hepatic lipid accumulation in PPARalpha (+/-):LDLR (+/-) mice, an obese mouse model." in: Lipids, Vol. 43, Issue 4, pp. 301-12, (2008) (PubMed).

Lewin, de Jong, Schwerbrock, Hammond, Watkins, Combs, Coleman: "Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition." in: Biochimica et biophysica acta, Vol. 1781, Issue 6-7, pp. 352-8, (2008) (PubMed).

Bhattacharyya, Kotlo, Shukla, Danziger, Tobacman: "Distinct effects of N-acetylgalactosamine-4-sulfatase and galactose-6-sulfatase expression on chondroitin sulfates." in: The Journal of biological chemistry, Vol. 283, Issue 15, pp. 9523-30, (2008) (PubMed).

Eberlé, Hegarty, Bossard, Ferré, Foufelle: "SREBP transcription factors: master regulators of lipid homeostasis." in: Biochimie, Vol. 86, Issue 11, pp. 839-48, (2004) (PubMed).

Coleman, Lee: "Enzymes of triacylglycerol synthesis and their regulation." in: Progress in lipid research, Vol. 43, Issue 2, pp. 134-76, (2003) (PubMed).

Synonyms and alternative names related to GPAM

glycerol-3-phosphate acyltransferase, mitochondrial (GPAM), glycerol-3-phosphate acyltransferase, mitochondrial (gpam), glycerol-3-phosphate acyltransferase, mitochondrial (Gpam), Gpam, GPAT, GPAT1

Protein level used designations for GPAM

  • mitochondrial glycerol 3-phosphate acyltransferase
  • glycerol-3-phosphate acyltransferase, mitochondrial
  • GPAT-1
  • P90
  • glycerol-3-phosphate acyltransferase 1, mitochondrial
  • glycerol 3-phosphate acyltransferase, mitochondrial
  • GPAT
  • mitochondrial glycerol phosphate acyltransferase
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