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HERC2 Antibodies

(Hect Domain and RLD 2 (HERC2))
This gene belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16. [provided by RefSeq, Mar 2012].

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Featured HERC2 Categories

HERC2 Antibodies

High quality antibodies with extensive validation data.

Recommended HERC2 Antibodies

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Reactivity Chicken, Cow, Dog, Human, Mouse, Rat, Xenopus laevis, Zebrafish (Danio rerio)
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Cat. No. ABIN2741335
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Cat. No. ABIN7095248
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Latest Publications for our HERC2 products

Ji, Rebert, Joslin, Higgins, Schultz, Nicholls: "Structure of the highly conserved HERC2 gene and of multiple partially duplicated paralogs in human." in: Genome research, Vol. 10, Issue 3, pp. 319-29, (2000) (PubMed).

Lehman, Nakatsu, Ching, Bronson, Oakey, Keiper-Hrynko, Finger, Durham-Pierre, Horton, Newton, Lyon, Brilliant: "A very large protein with diverse functional motifs is deficient in rjs (runty, jerky, sterile) mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 16, pp. 9436-41, (1998) (PubMed).

Synonyms and alternative names related to HERC2

HECT and RLD domain containing protein 2 (HERC2), HECT and RLD domain containing E3 ubiquitin protein ligase 2 (Herc2), HECT and RLD domain containing E3 ubiquitin protein ligase 2 (HERC2), CG11734, D7H15F32S1, D7H15F37S1, D15F32S1h, D15F37S1, Dmel\\CG11734, jdf2, mKIAA0393, p528, rjs, SHEP1

Protein level used designations for HERC2

  • CG11734-PC
  • HERC2-PC
  • E3 ubiquitin-protein ligase HERC2
  • HECT domain and RCC1-like domain-containing protein 2
  • probable E3 ubiquitin-protein ligase HERC2
  • hect domain and RCC1-like domain-containing protein 2
  • hect domain and RLD 2
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