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HPS3 Products

(Hermansky-Pudlak Syndrome 3 (HPS3))

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This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined. [provided by RefSeq, Jul 2008].

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Featured HPS3 Categories

HPS3 Antibodies

High quality antibodies with extensive validation data.

HPS3 ELISA Kits

Reliable ELISA kits for a wide range of species.

HPS3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HPS3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (3)
Cat. No. ABIN2856536
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1539245
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN185260
Quantity 100 μg
Datasheet Datasheet

Recommended HPS3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1743198
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774103
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method
Validations
Cat. No. ABIN1769207
Quantity 96 tests
Datasheet Datasheet

Recommended HPS3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307042
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307044
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092978
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HPS3 products

Dennis, Mantegazza, Snir, Tenza, Acosta-Ruiz, Delevoye, Zorger, Sitaram, de Jesus-Rojas, Ravichandran, Rux, Sviderskaya, Bennett, Raposo, Marks, Setty: "BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery." in: The Journal of cell biology, Vol. 209, Issue 4, pp. 563-77, (2015) (PubMed).

Gautam, Chintala, Li, Zhang, Tan, Novak, Di Pietro, DellAngelica, Swank: "The Hermansky-Pudlak syndrome 3 (cocoa) protein is a component of the biogenesis of lysosome-related organelles complex-2 (BLOC-2)." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12935-42, (2004) (PubMed).

Synonyms and alternative names related to HPS3

HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 L homeolog (hps3.L), HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 (Hps3), Hermansky-Pudlak syndrome 3 (Hps3), coa, HPS3, SUTAL

Protein level used designations for HPS3

  • Hermansky-Pudlak syndrome 3 protein
  • Hermansky-Pudlak syndrome 3
  • Hermansky-Pudlak syndrome 3 homolog
  • Hermansky-Pudlak syndrome 3 protein homolog
  • cocoa protein
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