HSPD1 Products
(Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
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This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010].
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Featured HSPD1 Categories
HSPD1 Antibodies
High quality antibodies with extensive validation data.
HSPD1 ELISA Kits
Reliable ELISA kits for a wide range of species.
HSPD1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended HSPD1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Pig, Rat
Application
WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
- (4)
- (7)
Cat. No.
ABIN726080
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, FACS, ELISA, IP
Validations
- (6)
- (6)
Cat. No.
ABIN361785
Quantity
200 μg
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, IHC, FACS, ELISA, ICC
Validations
- (2)
- (6)
Cat. No.
ABIN969200
Quantity
100 μL
Datasheet
Datasheet
Recommended HSPD1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
Cat. No.
ABIN6574222
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
Cat. No.
ABIN6574223
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6956400
Quantity
96 tests
Datasheet
Datasheet
Recommended HSPD1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Bacteria
Source
Escherichia coli (E. coli)
Validations
- (2)
- (1)
Cat. No.
ABIN1686691
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123268
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123267
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our HSPD1 products
: "Top3α is the replicative topoisomerase in mitochondrial DNA replication." in: Nucleic acids research, Vol. 50, Issue 15, pp. 8733-8748, (2022) (PubMed).: "Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation." in: Life science alliance, Vol. 3, Issue 1, (2020) (PubMed).
: "Activation of mitochondrial unfolded protein response is associated with Her2-overexpression breast cancer." in: Breast cancer research and treatment, Vol. 183, Issue 1, pp. 61-70, (2020) (PubMed).
: "Trimetazidine Improves the Outcome of EECP Therapy in Patients with Refractory Angina Pectoris." in: Medical archives (Sarajevo, Bosnia and Herzegovina), Vol. 74, Issue 3, pp. 199-204, (2020) (PubMed).
: "Frataxin-deficient neurons and mice models of Friedreich ataxia are improved by TAT-MTScs-FXN treatment." in: Journal of cellular and molecular medicine, Vol. 22, Issue 2, pp. 834-848, (2019) (PubMed).
: "Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2." in: Nucleic acids research, Vol. 46, Issue 18, pp. 9625-9636, (2019) (PubMed).
: "Low Intensity Focused Ultrasound (LOFU)-mediated Acoustic Immune Priming and Ablative Radiation Therapy for in situ Tumor Vaccines." in: Scientific reports, Vol. 9, Issue 1, pp. 15516, (2019) (PubMed).
: "Modulation of Diacylglycerol-Induced Melanogenesis in Human Melanoma and Primary Melanocytes: Role of Stress Chaperone Mortalin." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2019, pp. 9848969, (2019) (PubMed).
: "Hsp60 exerts a tumor suppressor function by inducing cell differentiation and inhibiting invasion in hepatocellular carcinoma." in: Oncotarget, Vol. 7, Issue 42, pp. 68976-68989, (2018) (PubMed).
: "Heat Shock Protein 60 in Obesity: Effect of Bariatric Surgery and its Relation to Inflammation and Cardiovascular Risk." in: Obesity (Silver Spring, Md.), Vol. 25, Issue 12, pp. 2108-2114, (2018) (PubMed).
Synonyms and alternative names related to HSPD1
heat shock protein family D (Hsp60) member 1 (HSPD1), heat shock protein family D (Hsp60) member 1 S homeolog (hspd1.S), heat shock protein family D (Hsp60) member 1 (hspd1), 60 kDa heat shock protein, mitochondrial (LOC100414401), heat shock protein 1 (chaperonin) (Hspd1), Heat shock protein 60A (Hsp60A), heat shock 60 protein 1 (hspd1), chaperone ATPase HSP60 (HSP60), molecular chaperone GroEL (groEL), thermosome subunit (MMP_RS07785), molecular chaperone GroEL (groEl), chaperonin GroEL (groEL), mitochondrial chaperonin (HSP60), 60 kDa heat shock protein, mitochondrial (LOC100136430), heat shock protein family D member 1 (Hspd1), heat shock protein family D (Hsp60) member 1 (Hspd1), 12, 60kDa, BP5, cb863, CG12101, chaperonin, CPN60, cpn60, Cpn60, crpA, d-hsp60, Dmel\\CG12101, Dmhsp60, fa04a05, fb22d10, fi27b05, G62, GROEL, groel, groL, HLD4, hld4, HSP-60, HSP60, hsp60, Hsp60, HSP60A, Hsp60A, hsp60A, HSP65, hsp65, Hspd1-30p, HuCHA60, id:ibd2197, IEF16, l(1)10Ac, l(1)BP5, l(1)dp025, l(1)G8, l(1)HM21, l(1)L12, MIF4, Mmp-P1, MNA2, mopA, sb:cb144, SPG13, spg13, SSP 7506, wu:fa04a05, wu:fb22d10, wu:fi04a12, wu:fi27b05Protein level used designations for HSPD1
- 60 kDa chaperonin
- 60 kDa heat shock protein, mitochondrial
- P60 lymphocyte protein
- chaperonin 60
- heat shock protein 65
- mitochondrial matrix protein P1
- short heat shock protein 60 Hsp60s1
- chaperonin
- heat shock 60 kDa protein 1
- mitochondrial heat shock 60 kDa protein 1
- CPN60
- HSP-60
- heat shock protein 60
- hsp60
- heat shock 60kDa protein 1 (chaperonin)
- 60 kDa heat shock protein, mitochondrial-like
- HSP-65
- heat shock protein, 60 kDa
- 60-kDa heat shock protein, mitochondrial
- CG12101-PA
- CG12101-PB
- Hsp 60
- Hsp60-PA
- Hsp60-PB
- heat shock protein 60 kDa
- lethal(1)10Ac
- nbl
- no blastema
- chaperonin GroEL
- mitochondrial chaperonin
- heat shock 60kD protein 1 (chaperonin)
- heat shock 60kDa protein 1
- heat shock protein 60 (liver)
- LOW QUALITY PROTEIN: 60 kDa heat shock protein, mitochondrial
- HSP60
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