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IL-4 Proteins

(Interleukin 4 (IL4))
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

116 results :

IL4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274949
 
IL4 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274948
 
IL4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Catalog No. ABIN7274951
 
IL4 Origin: Mouse Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Catalog No. ABIN2018020
 
IL4 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Catalog No. ABIN2018117
 
IL4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Catalog No. ABIN7274950
 
IL4 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN3137668
 
IL4 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320597
 
IL4 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7538345
 
IL4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7491513
 
IL4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Catalog No. ABIN1307826
 
IL4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320599
 
IL4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95% by SDS-PAGE SDS, AcA Active
Catalog No. ABIN6387871
 
IL4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Catalog No. ABIN1307825
 
IL4 Origin: Mouse Recombinant BCA
Catalog No. ABIN1111749
 
IL4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % by SDS-PAGE Active
Catalog No. ABIN1589638
 
IL4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7504977
 
IL4 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 85 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505486
 
IL4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 98 % by SDS-PAGE and Coomassie stain Active
Catalog No. ABIN7539338
 
IL4 Origin: Rat Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2018118
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • ELISA
    • Western Blotting (WB)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Standard (STD)
    • Cell Culture (CC)
    • Protein Interaction (PI)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunoprecipitation (IP)
    • Biochemical Assay (BCA)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Pig
    • Cow
    • Cynomolgus
    • Dog
    • Goat
    • Horse
    • Rabbit
    • Sheep
    • Guinea Pig
    • Rhesus Monkey
    • Baboon
    • Boselaphus tragocamelus
    • Buffalo
    • Cat
    • Chicken
    • Chimpanzee
    • Golden Syrian Hamster
    • Llama
    • Monkey
    • Panda
    • Red Deer
    • Tursiops truncatus
    • White-eyelid mangabey (Cercocebus)
  • Images available
  • Preservative free only
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • CHO Cells
    • Mammalian Cells
    • Human Cells
    • Wheat germ
  • Binding Specificity
    • AA 25-153
    • AA 21-140
    • AA 1-153
    • AA 25-135
    • AA 25-133
    • Transcript Variant 1
    • AA 23-140
    • AA 25-147
    • AA 25-132
    • AA 61-111
    • AA 1-135
    • AA 1-147
    • AA 20-143
    • AA 20-147
    • AA 23-147
    • AA 24-132
    • AA 24-134
    • AA 25-144
    • AA 26-136
    • AA 26-147
    • AA 63-153
    • Monomer
    • full length
  • Conjugate
    • His tag
    • Un-conjugated
    • Fc Tag
    • His tag,GST tag
    • GST tag
    • His tag,AVI tag,Biotin
    • His-Avi Tag
    • His-Avi Tag,Biotin
    • His-SUMO Tag
    • Myc-DYKDDDDK Tag
    • mFc Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Grade
    • Animal-Free
    • MALS verified
  • Supplier
    • antibodies-online
    • CUSABIO
    • Rockland
    • Abbexa
    • OriGene
    • Cloud-Clone
    • ACROBiosystems
    • Signalway
    • ITSI-Biosciences

Latest Publications for our IL-4 Proteins

Huang, Yi, Hu, Du, Wang, Ye, Su, Kijlstra, Yang: "Linoleic acid inhibits in vitro function of human and murine dendritic cells, CD4+T cells and retinal pigment epithelial cells." in: Graefe's archive for clinical and experimental ophthalmology, (2020) (PubMed).

He, Wang, Su, Deng, Ye, Huang, Yuan, Aize, Li, Yang: "Decreased expression of A20 is associated with ocular Behcet's disease (BD) but not with Vogt-Koyanagi-Harada (VKH) disease." in: The British journal of ophthalmology, Vol. 102, Issue 8, pp. 1167-1172, (2019) (PubMed).

Yi, Chang, Hu, Qiu, Wang, Cao, Yuan, Su, Zhou, Wang, Kijlstra, Yang: "Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease." in: Investigative ophthalmology & visual science, Vol. 59, Issue 11, pp. 4662-4669, (2019) (PubMed).

Wang, Lin, Zeng, Ouyang, Ran, Yang, Liu: "Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells." in: Scientific reports, Vol. 7, Issue 1, pp. 8519, (2019) (PubMed).

Li, Huo, Fang, Zou, Gu, Tao, Xu: "ROCK Inhibitor Y27632 Induced Morphological Shift and Enhanced Neurite Outgrowth-Promoting Property of Olfactory Ensheathing Cells via YAP-Dependent Up-Regulation of L1-CAM." in: Frontiers in cellular neuroscience, Vol. 12, pp. 489, (2018) (PubMed).

Wang, Mo, Xiao, An, Liu, Ba, Wu, Ran, Yang, Liu: "Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model." in: Scientific reports, Vol. 7, pp. 43322, (2018) (PubMed).

Qiu, Yu, Zhu, Ye, Deng, Su, Cao, Yuan, Kijlstra, Yang: "Hypermethylation of Interferon Regulatory Factor 8 (IRF8) Confers Risk to Vogt-Koyanagi-Harada Disease." in: Scientific reports, Vol. 7, Issue 1, pp. 1007, (2017) (PubMed).

Tao, Yang, Jia, Wan, Cheng, Lu: "Molecular cloning, recombinant expression and characterization of GMCSF from the rhesus monkey, Macaca mulatta." in: Developmental and comparative immunology, Vol. 40, Issue 1, pp. 69-77, (2013) (PubMed).

Martinez-Navio, Casanova, Pacheco, Naval-Macabuhay, Climent, Garcia, Gatell, Mallol, Gallart, Lluis, Franco: "Adenosine deaminase potentiates the generation of effector, memory, and regulatory CD4+ T cells." in: Journal of leukocyte biology, Vol. 89, Issue 1, pp. 127-36, (2011) (PubMed).

Bosco, McKenna, Firth, Sly, Holt: "A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 10, pp. 6011-21, (2009) (PubMed).

Aliases for IL-4 Proteins

interleukin 4 (IL4) Proteins
interleukin 4 (Il4) Proteins
BCGF-1 Proteins
BCGF1 Proteins
BSF-1 Proteins
BSF1 Proteins
IL-4 Proteins
Il-4 Proteins
IL2 Proteins
IL4 Proteins
Il4e12 Proteins
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