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INSL3 Products

(Insulin-Like 3 (Leydig Cell) (INSL3))
This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012].

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Featured INSL3 Categories

INSL3 Antibodies

High quality antibodies with extensive validation data.

INSL3 ELISA Kits

Reliable ELISA kits for a wide range of species.

INSL3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended INSL3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7189410
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IF
Validations
  • (2)
Cat. No. ABIN7074302
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN1493377
Quantity 100 μg
Datasheet Datasheet

Recommended INSL3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6956778
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6956777
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6967621
Quantity 96 tests
Datasheet Datasheet

Recommended INSL3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN1945456
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN7318736
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2723493
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our INSL3 products

Wang, Liu, Chang, Chen, An, Yan, Gao, Xu, Cui, Dong, Chen, Fan, Hu, Song, Zhu, Gao, Yao, Bian, Hou, Lu, Wang, Fan, Lian, Tang, Wang, Liu, Zhao, Wang, Liu, Yuan, Shi, Hu, Ren, Tang, Zhao, Qiao: "Single-Cell RNA Sequencing Analysis Reveals Sequential Cell Fate Transition during Human Spermatogenesis." in: Cell stem cell, Vol. 23, Issue 4, pp. 599-614.e4, (2018) (PubMed).

Hayashi, To, Saruta, Sato, Yamamoto, Kondo, Shimizu, Kamata, Tsukinoki: "Salivary lactoferrin is transferred into the brain via the sublingual route." in: Bioscience, biotechnology, and biochemistry, Vol. 81, Issue 7, pp. 1300-1304, (2017) (PubMed).

Komarowska, Milewski, Charkiewicz, Matuszczak, Sulewska, Zelazowska-Rutkowska, Hermanowicz, Niklinski, Debek, Hermanowicz: "Are anti-Müllerian hormone and its receptor polymorphism associated with the hormonal condition of undescended testes?" in: Advances in medical sciences, Vol. 61, Issue 2, pp. 288-292, (2016) (PubMed).

Yetim, Yetim, Baş, Erol, Çığ, Uçar, Darendeliler: "Anti-Müllerian Hormone and Inhibin-A, but not Inhibin-B or Insulin-Like Peptide-3, may be Used as Surrogates in the Diagnosis of Polycystic Ovary Syndrome in Adolescents: Preliminary Results." in: Journal of clinical research in pediatric endocrinology, Vol. 8, Issue 3, pp. 288-97, (2016) (PubMed).

Lardone, Argandoña, Flórez, Parada-Bustamante, Ebensperger, Palma, Piottante, Castro: "Overexpression of CYP19A1 aromatase in Leydig cells is associated with steroidogenic dysfunction in subjects with Sertoli cell-only syndrome." in: Andrology, Vol. 5, Issue 1, pp. 41-48, (2016) (PubMed).

Yang, Xue, Lu, Xie, Yin, Zheng, Sun, Li: "Induction of tolerance and prolongation of islet allograft survival by syngeneic hematopoietic stem cell transplantation in mice." in: Transplant immunology, Vol. 33, Issue 2, pp. 130-9, (2015) (PubMed).

Zhou, Chen, Chen, Wu, Wang, Wang: "The beneficial effects of betaine on dysfunctional adipose tissue and N6-methyladenosine mRNA methylation requires the AMP-activated protein kinase ?1 subunit." in: The Journal of nutritional biochemistry, (2015) (PubMed).

Nygaard, Almstrup, Lindbæk, Christensen, Svingen: "Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells." in: Scientific reports, Vol. 5, pp. 10364, (2015) (PubMed).

Djureinovic, Fagerberg, Hallström, Danielsson, Lindskog, Uhlén, Pontén: "The human testis-specific proteome defined by transcriptomics and antibody-based profiling." in: Molecular human reproduction, Vol. 20, Issue 6, pp. 476-88, (2014) (PubMed).

Foresta, Ferlin: "Role of INSL3 and LGR8 in cryptorchidism and testicular functions." in: Reproductive biomedicine online, Vol. 9, Issue 3, pp. 294-8, (2004) (PubMed).

Synonyms and alternative names related to INSL3

insulin like 3 (INSL3), insulin-like 3 (Insl3), Janus kinase 3 (JAK3), BLEYI-L, INSL3, ley-I-L, Ley-I-L, LEY I-L, Rlf, RLF, Rlnl, RLNL

Protein level used designations for INSL3

  • insulin-like 3
  • Ley I-L
  • ley-I-L
  • leydig insulin-like peptide
  • relaxin like factor
  • relaxin-like factor
  • Leydig insulin-like peptide relaxin-like factor
  • leydig insulin -like hormone
  • prepro-INSL3
  • relaxin-like factor b
  • insulin-like factor 3
  • Leydig insulin-like hormone
  • insulin-like peptide-3
  • insulin-like 3 (Leydig cell)
  • insulin-like peptide 3
  • insulin-like 3-like
  • Insulin-like 3
  • Relaxin-like factor
  • Leydig insulin-like peptide
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