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Triacsin C

Inh 76896-80-5 (3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane

Chemical structure of Triacsin C , a Fatty acyl-CoA synthase inhibitor. (Triacsin C)

1 image

Catalog No. ABIN1027762

Datasheet as PDF

Quick Overview for Triacsin C (ABIN1027762)

Application

Inhibition (Inh)

Chemical Name

(3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane

Purpose

Acyl-CoA synthetase inhibitor

Characteristics

Fatty acyl-CoA synthase inhibitor.

Purity

90 % (HPLC), NMR (Conforms).

Formula

C11H17N3O

Solubility

Soluble in DMSO (25 mg/ml) or methanol (5 mg/ml)
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

Geldanamycin- FITC
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

5-Azacytidine
Inh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

Nicotinamide
Inh 98-92-0 Pyridine-3-carboxylic acid amide

SAHA (Vorinostat)
Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid

Phenylbutyrate Na
Inh 1716-12-7 4-Phenylbutyric acid, sodium salt

CI-994
Inh 112522-64-2 4-(Acetylamino)-N-(2-aminophenyl)benzamide

Tranylcypromine hemisulfate (±)
Inh Cell-permeable 13492-01-8 Trans (±)-2-phenylcyclopropanamine, hemisulfate salt

Tenovin-1
Inh 380315-80-0 N-[(4-Acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide

Comment

Source: Synthetic.
Appearance: Oil dissolved in DMSO (1mg/ml)

Restrictions

For Research Use only
Format

Oil

Precaution of Use

Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Handling Advice

Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Storage

-20 °C
Background

Triacsin C is a potent inhibitor of long fatty acyl CoA synthetase. It blocks beta-cell apoptosis. It also blocks the de novo synthesis of triglyercides, diglycerides and cholesterol esters, interfering with lipid metabolism. It is also a potent vasodilator.

Molecular Weight

207.27

CAS-No

76896-80-5

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