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Hypericin

Inh 548-04-9 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
Catalog No. ABIN1027841
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Quick Overview for Hypericin (ABIN1027841)

Application

Inhibition (Inh)

Chemical Name

1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
  • Purpose

    Protein kinase C inhibitor

    Characteristics

    Protein kinase C inhibitor.

    Purity

    >98 %

    Formula

    C30H16O8

    Solubility

    Soluble to 10 mM in ethanol and to 50 mM in DMSO
  • Comment

    Source: Synthetic.
    Appearance: Dark Red Solid

    Restrictions

    For Research Use only
  • Format

    Solid

    Precaution of Use

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

    Handling Advice

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

    Storage

    -20 °C
  • Background

    Hypericin is a naphtodianthrone that acts as an antibiotic and non-specific kinase inhibitor. It inhibits the action of dopamine beta-hydroxylase, leading to increased dopamine levels. Hypericin can also cause photosensitivity when ingested beyond threshold. And becase it also accumulates in cancerous tissues, it can be used as an indicator of cancerous cells.

    Molecular Weight

    504.45

    CAS-No

    548-04-9
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