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Conantokin G

BR, InhA 93438-65-4
Catalog No. ABIN1540037
$376.92
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Quick Overview for Conantokin G (ABIN1540037)

Application

Blocking Reagent (BR), Inhibition Assay (InhA)
  • Purpose

    Conantokin G inhibits NMDA receptors

    Sequence

    Gly-Glu-Gla-Gla-Leu-Gln-Gla-Asn-Gln-Gla-Leu-Ile-Arg-Gla-Lys-Ser-Asn-NH2

    Specificity

    Conantokin G has been isolated from the venom of the cone Conus geographus. This toxin selectively inhibits NR2B subunits of N-methyl-D-aspartate (NMDA) receptor-mediated calcium influx in central nervous system neurons. Conantokin G induces sleep-like symptoms in young mice and hyperactivity in older mice (SERT).
  • Restrictions

    For Research Use only
  • Molecular Weight

    2264.23 Da

    CAS-No

    93438-65-4
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