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Carbaglu

InhA, Func 1188-38-1
Catalog No. ABIN3220322

Quick Overview for Carbaglu (ABIN3220322)

Application

Inhibition Assay (InhA), Functional Studies (Func)
  • Purpose

    Carglumic acid is an orphan drug used for the treatment of hyperammonaemia in patients with N-acetylglutamate synthase deficiency. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010.

    Characteristics

    Tradename: Zemuron
    Source of Compound: synthetic
    Target: Amino Acids and Derivatives
    Receptor: Carbamoyl-phosphate synthase

    Purification

    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.

    Purity

    98 %

    Formula

    C6H10N2O5

    Solubility

    10 mM in H2O
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Solid

    Storage

    -20 °C

    Storage Comment

    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.

    Expiry Date

    24 months
  • Background

    Amino Acids & Building Blocks

    Molecular Weight

    190.15 g/mol

    CAS-No

    1188-38-1
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