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Y 27632

Inh 146986-50-7 Y-27632 dihydrochloride, (R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide . 2HCl

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Catalog No. ABIN5022791

Quick Overview for Y 27632 (ABIN5022791)

Application

Inhibition (Inh)

Chemical Name

Y-27632 dihydrochloride, (R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide . 2HCl

Purpose

ROCK kinase inhibitor

Purity

≥98 % (HPLC)

Formula

C14H23Cl2N3O

Solubility

Soluble in DMSO (25 mg/ml), methanol (25 mg/ml), acetonitrile (<1 mg/ml), dioxan (<1 mg/ml), water (very soluble
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Comment

Source: Synthetic.
Appearance: White to pale yellow powder

Restrictions

For Research Use only
Format

Powder

Precaution of Use

Classification: Acute toxicity, Oral (Category 4), H302 Acute toxicity, Inhalation (Category 4), H332 Acute toxicity, Dermal (Category 4), H312 Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled Precautionary statements: P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ protective clothing. P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P312 Call a POISON CENTER or doctor/ physician if you feel unwell. P322 Specific measures (see supplemental first aid instructions on this label). P330 Rinse mouth. P363 Wash contaminated clothing before reuse. P501 Dispose of contents/ container to an approved waste disposal plant.

Handling Advice

Classification: Acute toxicity, Oral (Category 4), H302 Acute toxicity, Inhalation (Category 4), H332 Acute toxicity, Dermal (Category 4), H312 Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled Precautionary statements: P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ protective clothing. P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P312 Call a POISON CENTER or doctor/ physician if you feel unwell. P322 Specific measures (see supplemental first aid instructions on this label). P330 Rinse mouth. P363 Wash contaminated clothing before reuse. P501 Dispose of contents/ container to an approved waste disposal plant.

Storage

-20 °C
Molecular Weight

320.3

CAS-No

146986-50-7