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Homotaurine

InhA, Func 3687-18-1

Homotaurine (Homotaurine)

1 image

Catalog No. ABIN3220198

Quick Overview for Homotaurine (ABIN3220198)

Application

Inhibition Assay (InhA), Functional Studies (Func)

Purpose

Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.

Characteristics

Source of Compound: synthetic
Target: Beta Amyloid,GABAR agonist
Receptor: Amyloid β ,GABA

Purification

All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.

Purity

97 %

Formula

C3H9NO3S

Solubility

10 mM in DMSO
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Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Solid

Storage

-20 °C

Storage Comment

For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.

Expiry Date

24 months
Background

Neuroscience

Molecular Weight

139.17 g/mol

CAS-No

3687-18-1

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