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AR-A014418

InhA, Func 487021-52-3
Catalog No. ABIN3220104

Quick Overview for AR-A014418 (ABIN3220104)

Application

Inhibition Assay (InhA), Functional Studies (Func)
  • Purpose

    AR-A014418 is an ATP-competitive, and selective GSK3β inhibitor with IC50 and Ki of 104 nM and 38 nM in cell-free assays, without significant inhibition on 26 other kinases tested.

    Characteristics

    Target: GSK-3 inhibitor
    Receptor: GSK3β

    Purification

    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.

    Purity

    98 %

    Formula

    C12H12N4O4S

    Solubility

    100 mM in DMSO
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Solid

    Storage

    -20 °C

    Storage Comment

    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.

    Expiry Date

    24 months
  • Background

    PI3K/Akt/mTOR Signaling

    Molecular Weight

    308.31 g/mol

    CAS-No

    487021-52-3
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