Application: Inhibition Assay (InhA), Functional Studies (Func)
Purpose: Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. For epilepsy it is used to treat partial seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Lamotrigine also acts as a mood stabilizer. It is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. Chemically unrelated to other anticonvulsants, lamotrigine has relatively few side-effects and does not require blood monitoring. The exact way lamotrigine works is unknown.
Characteristics: Tradename: LAMICTAL
Source of Compound: synthetic, BW-430C
Target: 5-HT receptor antagonist,Sodium Channel inhibitor
Receptor: 5-HT receptor, Sodium channel
Purification: All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity: 98 %
Formula: C9H7Cl2N5
Solubility: Soluble in water

Geldanamycin

Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol

Inh 12772-57-5

Geldanamycin- FITC

Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Nicotinamide

Inh 98-92-0 Pyridine-3-carboxylic acid amide

5-Azacytidine

Inh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

SAHA (Vorinostat)

Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid

Phenylbutyrate Na

Inh 1716-12-7 4-Phenylbutyric acid, sodium salt

CI-994

Inh 112522-64-2 4-(Acetylamino)-N-(2-aminophenyl)benzamide

Tranylcypromine hemisulfate (±)

Inh Cell-permeable 13492-01-8 Trans (±)-2-phenylcyclopropanamine, hemisulfate salt

Tenovin-1

Inh 380315-80-0 N-[(4-Acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide

Application Notes: Optimal working dilution should be determined by the investigator.
Restrictions: For Research Use only

Format: Solid
Storage: -20 °C
Storage Comment: For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date: 24 months

Background: Membrane Transporter/Ion Channel,Neuroscience
Molecular Weight: 256.09 g/mol
CAS-No: 84057-84-1

Lamotrigine

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