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ISG15 Products

(ISG15 Ubiquitin-Like Modifier (ISG15))

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The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012].

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Featured ISG15 Categories

ISG15 Antibodies

High quality antibodies with extensive validation data.

ISG15 ELISA Kits

Reliable ELISA kits for a wide range of species.

ISG15 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ISG15 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (9)
Cat. No. ABIN7430072
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (7)
Cat. No. ABIN3021653
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (5)
  • (4)
Cat. No. ABIN387983
Quantity 400 μL
Datasheet Datasheet

Recommended ISG15 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6961959
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957216
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6973820
Quantity 96 tests
Datasheet Datasheet

Recommended ISG15 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN666864
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308133
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308131
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our ISG15 products

Alcalá, Sancho, Martinelli, Navarro, Pedrero, Martín-Hijano, Valle, Earl, Rodríguez-Serrano, Ruiz-Cañas, Rojas, Carrato, García-Bermejo, Fernández-Moreno, Hermann, Sainz: "ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity." in: Nature communications, Vol. 11, Issue 1, pp. 2682, (2020) (PubMed).

Cheriyamundath, Basu, Haase, Doernberg, Gavert, Brabletz, Ben-Zeev: "ISG15 induction is required during L1-mediated colon cancer progression and metastasis." in: Oncotarget, Vol. 10, Issue 67, pp. 7122-7131, (2019) (PubMed).

Speer, Li, Buta, Payelle-Brogard, Qian, Vigant, Rubino, Gardner, Wedeking, Hermann, Duehr, Sanal, Tezcan, Mansouri, Tabarsi, Mansouri, Francois-Newton, Daussy, Rodriguez, Lenschow, Freiberg et al.: "ISG15 deficiency and increased viral resistance in humans but not mice. ..." in: Nature communications, Vol. 7, pp. 11496, (2018) (PubMed).

Gall, Pryke, Abraham, Mizuno, Botto, Sali, Broeckel, Haese, Nilsen, Placzek, Morrison, Heise, Streblow, DeFilippis: "Emerging Alphaviruses Are Sensitive to Cellular States Induced by a Novel Small-Molecule Agonist of the STING Pathway." in: Journal of virology, Vol. 92, Issue 6, (2018) (PubMed).

Yamada, Nakaoka, Klein, Reith, Langer, Hopfensperger, Iwami, Schreiber, Kirchhoff, Koyanagi, Sauter, Sato: "Human-Specific Adaptations in Vpu Conferring Anti-tetherin Activity Are Critical for Efficient Early HIV-1 Replication In Vivo." in: Cell host & microbe, Vol. 23, Issue 1, pp. 110-120.e7, (2018) (PubMed).

Johnson, Lucas, Amon, Skelton, Nazitto, Carbonetti, Sather, Littman, Aderem: "Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection." in: Cell host & microbe, Vol. 23, Issue 3, pp. 366-381.e9, (2018) (PubMed).

Katzenell, Leib: "Herpes simplex virus and interferon signaling induce novel autophagic clusters in sensory neurons." in: Journal of virology, (2016) (PubMed).

Huang, Bulavin: "Oncogene-mediated regulation of p53 ISGylation and functions." in: Oncotarget, Vol. 5, Issue 14, pp. 5808-18, (2015) (PubMed).

Ezzati, Komher, Severini, Coombs: "Comparative proteomic analyses demonstrate enhanced interferon and STAT-1 activation in reovirus T3D-infected HeLa cells." in: Frontiers in cellular and infection microbiology, Vol. 5, pp. 30, (2015) (PubMed).

Zaheer, Wiehler, Hudy, Traves, Pelikan, Leigh, Proud: "Human rhinovirus-induced ISG15 selectively modulates epithelial antiviral immunity." in: Mucosal immunology, Vol. 7, Issue 5, pp. 1127-38, (2014) (PubMed).

Synonyms and alternative names related to ISG15

ISG15 ubiquitin-like modifier (ISG15), ISG15 ubiquitin-like modifier (isg15), ISG15 ubiquitin-like modifier (Isg15), G1P2, g1p2, G1p2, hUCRP, IFI15, IGI15, IP17, Irfp, ISG15, ISG17, ISG17/UCRP, si:rp71-1c23.2, UCRP

Protein level used designations for ISG15

  • interferon, alpha-inducible protein (clone IFI-15K)
  • interferon-induced 17-kDa/15-kDa protein
  • interferon-stimulated protein, 15 kDa
  • ubiquitin cross-reactive protein
  • ubiquitin-like protein ISG15
  • boUCRP
  • interferon-stimulated gene product 17
  • ISG15 ubiquitin-like modifier
  • si:rp71-1c23.2
  • zfISG15
  • interferon stimulated gene, 15 kDa
  • interferon, alpha-inducible protein
  • interferon-induced 17 kDa protein
  • interferon-stimulated protein 15
  • interferon-induced 15 kDa protein
  • interferon-induced 15-KDa protein
  • interferon-stimulated protein (15 kDa)
  • interferon stimulated gene 17
  • interferon-stimulated protein 17/ubiquitin cross-reactive protein
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