Rat IgG Isotype Control

Details for Product No. ABIN964381, Supplier: Log in to see
Isotype
Host
Rat
177
174
172
139
126
116
82
67
64
62
56
52
51
47
33
22
16
15
11
7
7
4
3
Antibody Type
Native
Application
Isotype Control (IsoC), ELISA, Western Blotting (WB)
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Isotype IgG
Fragment Fc fragment
Characteristics Concentration Definition: by UV absorbance at 280 nm
Isotype
Background Secreted as part of the adaptive immune response by plasma B cells, immunoglobulin G constitutes 75 % of serum immunoglobulins. Immunoglobulin G binds to viruses, bacteria, as well as fungi and facilitates their destruction or neutralization via agglutination (and thereby immobilizing them), activation of the compliment cascade, and opsinization for phagocytosis. The F(c) fragment binds with very high affinity to the Fc receptor proteins on phagocytic leukocytes. When digested from the whole antibody molecule, the F(c) fragment no longer posses the epitope recognition site.

Synonyms: Rat Immunoglobulin G F(c) fragment, IgG Fc
Application Notes Rat IgG F(c) Fragment can be utilized as a control or standard reagent in Western Blotting and ELISA experiments.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Storage 4 °C
Supplier Images
SDS-PAGE (SDS) image for Rat IgG isotype control (ABIN964381) SDS-PAGE of Rat IgG F(c) Fragment . Lane M: 3 µL Opal Prestained Marker . Lane 1: Red...
SDS-PAGE (SDS) image for Rat IgG isotype control (ABIN964381) SDS-Page of Rat IgG F(c). Lane 1: Rat Fc – Non-reduced. Lane 2: Rat Fc - Reduced. Loa...