Browse our anti-PIAS2 (PIAS2) Antibodies

Full name:: anti-Protein Inhibitor of Activated STAT, 2 Antibodies (PIAS2)

On www.antibodies-online.com are 127 Protein Inhibitor of Activated STAT, 2 (PIAS2) Antibodies from 24 different suppliers available. Additionally we are shipping PIAS2 Proteins (5) and many more products for this protein. A total of 159 PIAS2 products are currently listed.

Synonyms:: 6330408K17Rik, AI462206, ARIP3, AU018068, Dib, DIP, MGC83751, MIZ, MIZ1, PIAS2, PIASX, PIASX-ALPHA, PIASX-BETA, PIASxalpha, PIASxb, PIASxbeta, SIZ2, wu:fi05f09, ZMIZ4

list all antibodies	Gene Name	GeneID	UniProt
	PIAS2	17344	Q8C5D8
	PIAS2	9063	O75928
	PIAS2	83422	Q6AZ28
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Most Popular Reactivities for anti-PIAS2 (PIAS2) Antibodies

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anti-Mouse (Murine) PIAS2 Antibodies:

anti-Human PIAS2 Antibodies:

anti-Rat (Rattus) PIAS2 Antibodies:

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Relevant Pathways for anti-PIAS2 Antibodies

Regulation of Intracellular Steroid Hormone Receptor Signaling

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Top referenced anti-PIAS2 Antibodies

Human Polyclonal PIAS2 Primary Antibody for IHC (p), IHC - ABIN252941 : van den Akker, Ano, Shih, Wang, Pironin, Palvimo, Kotaja, Kirsh, Dejean, Ghysdael: FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family. in The Journal of biological chemistry 2005 (PubMed)
Human Polyclonal PIAS2 Primary Antibody for ELISA, WB - ABIN4345419 : Saito, Novak, Piovan, Basso, Sumazin, Schneider, Crespo, Shen, Bhagat, Califano, Chadburn, Pasqualucci, Dalla-Favera: BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)

More Antibodies against PIAS2 Interaction Partners

Xenopus laevis Protein Inhibitor of Activated STAT, 2 (PIAS2) interaction partners

The Xenopus PIAS (show PIAS1 Antibodies) genes are expressed throughout early development and have overlapping and distinct expression patterns, with, for example, high levels of PIAS2 in the notochord.

Mouse (Murine) Protein Inhibitor of Activated STAT, 2 (PIAS2) interaction partners

A direct interaction between Pold2 (show POLD2 Antibodies) and PIAS2 was confirmed by direct yeast two-hybrid.
Interaction of protein inhibitor of activated STAT 2 (PIAS2) with receptor of activated C kinase 1, RACK1 (show GNB2L1 Antibodies).
regulates interleukin-7 receptor (show IL7R Antibodies) signaling at early commitment stages of B cell differentiation
a transcriptional cofactor for TFII-I (show GTF2I Antibodies)
Miz-1 (show ZBTB17 Antibodies) trans-actiates Nramp1 (show SLC11A1 Antibodies) in mice
Results show that Miz1 is required for early embryonic development during gastrulation.
Miz-1 (show ZBTB17 Antibodies) has a role in inducing apoptosis along with MAGE-A4 (show MAGEA4 Antibodies)
study provides the first line of evidence that PIASxbeta is indispensable for osteoblast differentiation and matrix mineralization, and that this signaling molecule is located between Runx2 (show RUNX2 Antibodies) and osterix (show SP7 Antibodies).

Human Protein Inhibitor of Activated STAT, 2 (PIAS2) interaction partners

strategy for the purification of tethered POZ domains that form forced heterodimers is described, and crystal structures of the heterodimeric POZ domains of Miz1 (show ZBTB17 Antibodies)/BCL6 (show BCL6 Antibodies) and of Miz1 (show ZBTB17 Antibodies)/NAC1 (show NACC1 Antibodies) are reported
the expression of SENP8 (show SENP8 Antibodies), SAE1 (show SAE1 Antibodies), PIAS1 (show PIAS1 Antibodies), PIAS2 and ZMIZ1 (show ZMIZ1 Antibodies) is deregulated in the majority of PTC (show F9 Antibodies) tissues, likely contributing to the PTC (show F9 Antibodies) phenotype.
UXT (show UXT Antibodies) is a binding protein of PIAS2, and interaction between PIAS2 and UXT (show UXT Antibodies) may be important for the transcriptional activation of AR.
PIASxalpha is a novel SUMO E3 ligase for PTEN, and it positively regulates PTEN protein level in tumor suppression.
These findings suggest that SUMO-1 (show SUMO1 Antibodies) modification of MDA5 (show IFIH1 Antibodies) possibly via PIAS2beta may play a role in the MDA5 (show IFIH1 Antibodies)-mediated interferon (show IFNA Antibodies) response to viral infections.
PIASx may function as a co-repressor of Stat4 (show STAT4 Antibodies)
Required for upregulation of a large group of genes in response to DNA damage, a function that is regulated by c-Myc (show MYC Antibodies), but not by 14-3-3eta and represses the expression of many genes
the repressive properties of PIASxalpha/ARIP3 require its physical interaction with FLI-1 (show FLI1 Antibodies), identifying PIASxalpha as a novel corepressor of FLI-1 (show FLI1 Antibodies)
findings show that Epstein-Barr virus Rta (show RBM9 Antibodies) interacts and colocalizes with PIASxalpha and PIASxbeta in the nucleus; these interactions seem to enhance Rta (show RBM9 Antibodies) sumoylation
PIASxalpha acts as a key signal integrator that permits different responses from the same transcription factor, depending on the signaling pathway that is activated.

PIAS2 Antigen Profile

Antigen Summary

This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.

Alternative names and synonyms associated with PIAS2

protein inhibitor of activated STAT 2 L homeolog (pias2.L) antibody
protein inhibitor of activated STAT 2 (PIAS2) antibody
protein inhibitor of activated STAT, 2 (pias2) antibody
protein inhibitor of activated STAT 2 (Pias2) antibody
protein inhibitor of activated STAT, 2 (Pias2) antibody

6330408K17Rik antibody
AI462206 antibody
ARIP3 antibody
AU018068 antibody
Dib antibody
DIP antibody
MGC83751 antibody
MIZ antibody
MIZ1 antibody
PIAS2 antibody
PIASX antibody
PIASX-ALPHA antibody
PIASX-BETA antibody
PIASxalpha antibody
PIASxb antibody
PIASxbeta antibody
SIZ2 antibody
wu:fi05f09 antibody
ZMIZ4 antibody

Protein level used designations for PIAS2

protein inhibitor of activated STAT, 2 , protein inhibitor of activated STAT X , protein inhibitor of activated STAT2 , E3 SUMO-protein ligase PIAS2 , E3 SUMO-protein ligase PIAS2-like , e3 SUMO-protein ligase PIAS2-like , DAB2-interacting protein , DIP , Msx-interacting-zinc finger , PIASxalpha6 , androgen receptor-interacting protein 3 , msx-interacting zinc finger protein , protein inhibitor of activated STAT x , zinc finger, MIZ-type containing 4 , ARIP3 , msx-interacting-zinc finger protein

GENE ID	SPECIES
432031	Xenopus laevis
455403	Pan troglodytes
564149	Danio rerio
696737	Macaca mulatta
100018269	Monodelphis domestica
100068879	Equus caballus
100073430	Ornithorhynchus anatinus
100391152	Callithrix jacchus
100466154	Ailuropoda melanoleuca
100584273	Nomascus leucogenys
100627995	Sus scrofa
17344	Mus musculus
9063	Homo sapiens
416383	Gallus gallus
480147	Canis lupus familiaris
83422	Rattus norvegicus
533403	Bos taurus

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Show all anti-Protein Inhibitor of Activated STAT, 2 (PIAS2) Antibodies with Pubmed References