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Browse our anti-PIAS2 (PIAS2) Antibodies

Full name:: anti-Protein Inhibitor of Activated STAT, 2 Antibodies (PIAS2)

On www.antibodies-online.com are 142 Protein Inhibitor of Activated STAT, 2 (PIAS2) Antibodies from 24 different suppliers available. Additionally we are shipping PIAS2 Proteins (5) and and many more products for this protein. A total of 172 PIAS2 products are currently listed.

Synonyms:: 6330408K17Rik, AI462206, ARIP3, AU018068, Dib, DIP, MGC83751, MIZ, MIZ1, PIAS2, PIASX, PIASX-ALPHA, PIASX-BETA, PIASxalpha, PIASxb, PIASxbeta, SIZ2, wu:fi05f09, ZMIZ4

list all antibodies	Gene Name	GeneID	UniProt
	PIAS2	17344	Q8C5D8
	PIAS2	9063	O75928
	PIAS2	83422	Q6AZ28
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Most Popular Reactivities for anti-PIAS2 (PIAS2) Antibodies

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anti-Mouse (Murine) PIAS2 Antibodies:

anti-Human PIAS2 Antibodies:

anti-Rat (Rattus) PIAS2 Antibodies:

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Relevant Pathways for anti-PIAS2 Antibodies

Regulation of Intracellular Steroid Hormone Receptor Signaling

More product categories related to PIAS2 Antibody

Top referenced anti-PIAS2 Antibodies

Human Polyclonal PIAS2 Primary Antibody for IHC (p), ELISA - ABIN542820 : Wu, Cetinkaya, Munoz-Alonso, von der Lehr, Bahram, Beuger, Eilers, Leon, Larsson: Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter. in Oncogene 2003 (PubMed)
Show all 3 Pubmed References
Human Polyclonal PIAS2 Primary Antibody for WB - ABIN6712018 : Yang, Zhao, Rasul, Qin, Li, Li: PIAS1-modulated Smad2/4 complex activation is involved in zinc-induced cancer cell apoptosis. in Cell death & disease 2013 (PubMed)
Dog (Canine) Polyclonal PIAS2 Primary Antibody for IHC (p), ELISA - ABIN547641 : van den Akker, Ano, Shih, Wang, Pironin, Palvimo, Kotaja, Kirsh, Dejean, Ghysdael: FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family. in The Journal of biological chemistry 2005 (PubMed)
Human Polyclonal PIAS2 Primary Antibody for ELISA, WB - ABIN4345419 : Saito, Novak, Piovan, Basso, Sumazin, Schneider, Crespo, Shen, Bhagat, Califano, Chadburn, Pasqualucci, Dalla-Favera: BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)

More Antibodies against PIAS2 Interaction Partners

Xenopus laevis Protein Inhibitor of Activated STAT, 2 (PIAS2) interaction partners

The Xenopus PIAS genes are expressed throughout early development and have overlapping and distinct expression patterns, with, for example, high levels of PIAS2 in the notochord.

Mouse (Murine) Protein Inhibitor of Activated STAT, 2 (PIAS2) interaction partners

A direct interaction between Pold2 and PIAS2 was confirmed by direct yeast two-hybrid.
Interaction of protein inhibitor of activated STAT 2 (PIAS2) with receptor of activated C kinase 1, RACK1.
regulates interleukin-7 receptor signaling at early commitment stages of B cell differentiation
role in activating natural resistance-associated protein 1 promoter
a transcriptional cofactor for TFII-I
Miz-1 trans-actiates Nramp1 in mice
Results show that Miz1 is required for early embryonic development during gastrulation.
Miz-1 has a role in inducing apoptosis along with MAGE-A4
study provides the first line of evidence that PIASxbeta is indispensable for osteoblast differentiation and matrix mineralization, and that this signaling molecule is located between Runx2 and osterix.

Human Protein Inhibitor of Activated STAT, 2 (PIAS2) interaction partners

the results presented demonstrate that in heat-stressed HeLa cells, p38 MAPK pathway-dependent SUMOylation of Elk-1 and phosphorylation of PIAS2 correlate with the downregulation of transactivation by Elk-1.
PIAS1expression of PIAS1 gene was increased in patients with MS compared to healthy subjects; also, there was a significant correlation between the expression of PIAS1 and PIAS2 genes with disease severity of multiple sclerosis
results indicated that PIAS2-mediated SUMOylation constrained HCV replication
the expression of SENP8, SAE1, PIAS1, PIAS2 and ZMIZ1 is deregulated in the majority of PTC tissues, likely contributing to the PTC phenotype.
UXT is a binding protein of PIAS2, and interaction between PIAS2 and UXT may be important for the transcriptional activation of AR.
PIASxalpha is a novel SUMO E3 ligase for PTEN, and it positively regulates PTEN protein level in tumor suppression.
These findings suggest that SUMO-1 modification of MDA5 possibly via PIAS2beta may play a role in the MDA5-mediated interferon response to viral infections.
PIASx may function as a co-repressor of Stat4
Required for upregulation of a large group of genes in response to DNA damage, a function that is regulated by c-Myc, but not by 14-3-3eta and represses the expression of many genes
the repressive properties of PIASxalpha/ARIP3 require its physical interaction with FLI-1, identifying PIASxalpha as a novel corepressor of FLI-1
findings show that Epstein-Barr virus Rta interacts and colocalizes with PIASxalpha and PIASxbeta in the nucleus; these interactions seem to enhance Rta sumoylation
PIASxalpha acts as a key signal integrator that permits different responses from the same transcription factor, depending on the signaling pathway that is activated.

PIAS2 Antigen Profile

Antigen Summary

This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1.

Alternative names and synonyms associated with PIAS2

protein inhibitor of activated STAT 2 L homeolog (pias2.L) antibody
protein inhibitor of activated STAT 2 (PIAS2) antibody
protein inhibitor of activated STAT, 2 (pias2) antibody
protein inhibitor of activated STAT 2 (Pias2) antibody
protein inhibitor of activated STAT, 2 (Pias2) antibody

6330408K17Rik antibody
AI462206 antibody
ARIP3 antibody
AU018068 antibody
Dib antibody
DIP antibody
MGC83751 antibody
MIZ antibody
MIZ1 antibody
PIAS2 antibody
PIASX antibody
PIASX-ALPHA antibody
PIASX-BETA antibody
PIASxalpha antibody
PIASxb antibody
PIASxbeta antibody
SIZ2 antibody
wu:fi05f09 antibody
ZMIZ4 antibody

Protein level used designations for PIAS2

protein inhibitor of activated STAT, 2 , protein inhibitor of activated STAT X , protein inhibitor of activated STAT2 , E3 SUMO-protein ligase PIAS2 , E3 SUMO-protein ligase PIAS2-like , e3 SUMO-protein ligase PIAS2-like , DAB2-interacting protein , DIP , Msx-interacting-zinc finger , PIASxalpha6 , androgen receptor-interacting protein 3 , msx-interacting zinc finger protein , protein inhibitor of activated STAT x , zinc finger, MIZ-type containing 4 , ARIP3 , msx-interacting-zinc finger protein

GENE ID	SPECIES
432031	Xenopus laevis
455403	Pan troglodytes
564149	Danio rerio
696737	Macaca mulatta
100018269	Monodelphis domestica
100068879	Equus caballus
100073430	Ornithorhynchus anatinus
100391152	Callithrix jacchus
100466154	Ailuropoda melanoleuca
100584273	Nomascus leucogenys
100627995	Sus scrofa
17344	Mus musculus
9063	Homo sapiens
416383	Gallus gallus
480147	Canis lupus familiaris
83422	Rattus norvegicus
533403	Bos taurus

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