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GDNF ELISA Kit

Mouse GDNF ELISA Kit Colorimetric assay for quantification of Mouse GDNF.
Catalog No. ABIN2042482

Quick Overview for GDNF ELISA Kit (ABIN2042482)

Target

See all GDNF ELISA Kits
GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

Reactivity

  • 13
  • 9
  • 9
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Mouse

Detection Method

Colorimetric

Method Type

Sandwich ELISA

Detection Range

31.2-2000 pg/mL

Application

ELISA
  • Minimum Detection Limit

    31.2 pg/mL

    Cross-Reactivity (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Sensitivity

    < 10 pg/mL

    Components

    96-well plate pre-coated with anti-GDNF, Mouse
    Lyophilized recombinant GDNF, Mouse standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • Plate

    Pre-coated

    Protocol

    Sandwich ELISA quantitative detection kit for Mouse GDNF in cell culture supernates, serum and plasma (heparin, EDTA).Glial cell line-derived neurotrophic factor (GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily.1 GDNF, is a potent neurotrophic factor that promotes the survival of dopaminergic neurones in cultures including embryonic neuronal cultures.2 GDNF, in addition to its potential role in the differentiation and survival of central nervous system neurons, has profound effects on kidney organogenesis and the development of the peripheral nervous system.3 GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons.

    Restrictions

    For Research Use only
  • Storage

    4 °C/-20 °C
  • Target See all GDNF ELISA Kits

    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

    Alternative Name

    GDNF

    Gene ID

    14573

    UniProt

    P48540

    Pathways

    RTK Signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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